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1、瞳蛇蛇伤致肾损害临床分析[摘要]目的研究圆斑嵯泰国亚种蛇伤伴发肾损伤的临床特点。方法回顾性分析2006年6月〜2013年12月住院的嵯蛇蛇伤患者的临床资料。根据病情予抗蛇毒血清、利尿、透析、中西医结合等多种治疗。观察患者蛇伤以及肾损害转归情况。结果嵯蛇蛇伤76例,发现尿蛋白阳性75例(98.7%),血清肌酹增高46例(60.5%),最高为1192Pmol/L,急性肾功能衰竭10例(13.2%)o蛇伤临床治愈61例(80.3%),显效13例(17.1%),死亡2例(2.6%),死亡原因为合并多脏器功能衰竭,直接死亡原因是呼吸循环衰竭,总有效率为97.4%o肾损害经治疗61例(80.3
2、%)2周内恢复,13例(17」%)半年内恢复。结论蛭蛇蛇伤肾损伤多见,临床上应常规进行尿检、血肌酹等检查以利于早期诊断。及时采取中西医结合方法治疗蛇伤所致的肾损害疗效确切。[关键词]圆斑嵯泰国亚种;嵯蛇蛇伤;蛇毒;肾损害[中图分类号]R595.8[文献标识码]B[文章编号]1674-4721(2014)05(c)-0188-03ClinicalanalysisofrenaldamageinducedbyVipersnakebiteZHONGHanZHONGJian-rongHEZhi-qiuYUPei-nanDepartmentofNephrology,theThirdPeople
3、7sHospitalofZhaoqingCityinGuangdongProvince,Zhaoqing526000,China[Abstract]ObjectiveTostudytheclinicalfeaturesofsnakebiteofViperarusselliiThailandsubspeciescomplicatedbyrenaldamage・MethodsClinicalinformationofthepatientswithVipersnakebitehospitalizedfromJune2006toDecember2013wasanalyzedretrospe
4、ctively.Multipletreatmentincludingantivenin,diuresis,dialysisandthetreatmentofintegratedtraditionalChineseandwesternmedicinewasgivenbasedonthestateofillness.Thesnakebiteandoutcomesofrenaldamagewereobserved.ResultsAmong76patientswithsnakebite,positiveurineproteinwasobservedin75patients(98.7%),s
5、erumcreatinineincreasingwasobservedin46patients(60.5%),withthemaximumof1192(imol/L?andacuterenalfunctionfailurewasobservedin10patients(13.2%).Regardingtosnakebite,61patients(80.3%)wereclinicallycured,13patients(17.1%)wereremarkablyeffectiveand2patients(2.6%)died.Thecauseofdeathwasthecomplicati
6、onofmultipleorganfailureandthedirectcauseofdeathwasrespiratorycirculationfailure,thetotaleffectiveratewas97.4%.Regardingtorenaldamage,61patients(80.3%)recoveredwithin2weeksoftreatmentand13patients(17.1%)recoveredwithin6monthsoftreatment.ConclusionRenaldamageinducedbyVipersnakebiteiscommonlysee
7、n,clinicalexaminationsincludingroutineurinalysisandserumcreatinineexaminationshouldbeconductedforthepurposeofearlydiagnosis.Timelyadoptionofintegrativemedicineshowsaccurateefficacyinthetreatmentofrenaldamageinducedbysnakebite・[Keywords]