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1、中国医学影像技术2010年第26卷第8期ChinJMedImagingTechnol,2010,Vol26,No8∀1441∀头颈部影像学Valueofcontrastenhancedultrasonographyindifferentialdiagnosisofbenignormalignantthyroidnodules*ZHAOYing,HUANGDaozhong,HUANGXiaoli(DepartmentofMedicalUltrasound,TongjiHospitalofTon
2、gjiMedicalCollegeofHuazhongUniversityofScience&Technology,Wuhan430030,China)[Abstract]ObjectiveToinvestigatethevalueofcontrastenhancedultrasonography(CEUS)inthedifferentialdiagnosisofbenignormalignantthyroidnodules.MethodsColorDopplerflowimaging(CDF
3、I)andcontrastenhancedultrasonographyperfusionof39thyroidnoduleswereretrospectivelyanalyzed.Thefillingintensityofbothperipheryandinteriorofthenodulebythetimeintensitycurve(TIC)wasobserved.Theevaluatedparametersincludedpeakintensity(PI)oftheperiphery,
4、interiorintensity(II)atthePItime,thedifferenceofPIandI(I).Thenthediagnosticcutofpointsforthyroidbenignormalignantthyroidnoduleswascalculated.ResultsMostofthemalignantthyroidnoduleswerefilledSonoVuepervasively(9412%).Mostofthebenignthyroidnodulessh
5、owedearlywashinoftheperiphery(8636%),andthemajorityshowedringenhancementatperiphery,slightornoneenhancementininterior.ItwaspronetobenignnodulewhenI>608dB,andthesensitivitywas8571%.Simultaneously,itwaspronetomalignantnodulewhenI<289dBandthesensitiv
6、itywas8235%.ConclusionCEUSisvaluableinthedifferentialdiagnosisofbenignormalignantthyroidnodules.[Keywords]Thyroidnodule;Ultrasonography;Contrastmedia;Timeintensitycurve超声造影鉴别诊断甲状腺结节良恶性的价值*赵莹,黄道中,黄小莉(华中科技大学同济医学院附属同济医院超声影像科,湖北武汉430030)[摘要]目的探讨超声造
7、影对鉴别诊断甲状腺结节良恶性的价值。方法回顾性分析39个甲状腺结节的彩色多普勒血流显像及超声造影灌注过程,观察病灶周边及内部造影剂灌注强度,通过时间强度曲线分析,比较病灶周边感兴趣区(ROI)峰值强度(PI)与达峰时刻病灶内部ROI相对应的造影剂灌注强度(II)的差异程度,计算两者差值I及诊断良、恶性结节的I分界值。结果甲状腺恶性结节造影增强模式多为弥漫性整体增强(9412%),良性结节多为周边先于内部增强(8636%),并以周边环状增强为主,内部轻微增强或始终无增强。初步界定I>6
8、08dB时,良性结节可能性大,敏感度为8571%;I<289dB时,恶性结节可能性大,敏感度为8235%。结论超声造影对鉴别甲状腺结节的良恶性有一定实用价值。[关键词]甲状腺结节;超声检查;造影剂;时间强度曲线[中图分类号]R7361;R4451[文献标识码]A[文章编号]10033289(2010)08144103甲状腺癌是浅表器官中常见的恶性肿瘤之一,女性多见,1资料与方法临床症状不典型,疾病的预后依赖于早期
