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1、中国中西医结合外科杂志2002年10月第8卷第5期335中药活血化瘀配合华法林钠治疗下肢深静脉血栓形成的临床研究宋红法,董淼伟,王庆宣,熊家锐,刘艳芳,王克金摘要:目的探讨中药活血化瘀与华法林钠对下肢深静脉血栓形成的疗效。方法把71例病人随机分为A、B两组。A组给予中药煎汤另服华法林钠,使血浆凝血酶原时间保持在正常的15倍左右;B组不用华法林钠,其余治疗同A组。6d为1疗程。治疗前后观察双下肢周径差,并行彩色多普勒、下肢静脉造影及血流变学检查对比。结果A组全部治愈,B组治愈率97.1%,A组治愈疗程短于B组;两组部分血流变指标在治疗前后有显著或非常显著的差别。结论中药
2、活血化瘀治疗DVT疗效明显,加用华法林钠效果更加显著。关键词:血栓形成;下肢深静脉;活血化瘀;中药治疗;华法林钠TreatmentofDeepVeinThrombusofLegsbyCombinationofHerbswithEffectsofActivatingBloodCirculationandDispersingStasisandWarfarinSodiumSongHongfa,DongMiaowei,WangQingxuan,etalNo.151HospitaloftheP.L.A,Anyang,Henan,Province(455002)Objective:Tos
3、tndythetherapeuticeffectfordeepveinthrombus(DVT)inlegs,bycombinationofherbswitheffectsofactivatingbloodcirculationanddispersingstasisandWarfarinSodiiumTabletsMethods:The71regularpatientsweredividedintoAandBgroupsrandomly.GroupAwasgivenherbalmedicinesouptogetherwithWarfarinSodiumTablets,keepi
4、ngplasmathrombinogentimeat1.5timesasnormal.GroupBwasgivenherbalmedicinebutnoWarfarintablets.Acourseoftreamentwassixdays.Beforeandaftertreatment,thedifferenceofperimetryofbothlegswereobservedandcolourDopplerandvenographyandrheclogicexaminationsmade.Results:AllpatientsingroupAwerecuredandthose
5、ingroupBhadacurerateof97.1%.ThetherapeuticcourseingroupAwasshorterthanthatinGroupB.Sanetheologicparametersshowedmarkedorverymarkeddifferencesbeforeandaftertreament.HerbalmedicinewitheffectsofactivatingbloodcirculationanddispersingstasisismarkedlyeffectiveinthetreatmentofDVT,andcombinationofW
6、arfarinSodiumtabletswillhavemoremarkedeffects.KeyWords:thrombosis;decpveinoflowerextremities;ativatingbloodcirculationanddispersingstasis;WarfarinSodiumtablets下肢深静脉血栓形成(deepveinthrombus,DVT)为例,B组35例。临床常见病,作者采用中药活血化瘀配合华法林钠治1.2治疗方法A组采用中药活血化瘀治疗,加服疗71例,收到了满意的临床效果,总结报告如下。华法林钠,使血浆凝血酶原时间保持在正常值的
7、1资料与方法15倍左右。B组不用华法林钠,其它治疗同A组。1.1一般资料男26例,女45例;年龄17~67岁,中药基本方:当归15g川芎12g桃仁12g红花平均46.8岁。78条肢体受累,左下肢58条,右下肢10g乌梢蛇20g柴胡12g牛膝15g木瓜20条;双下肢7例。合并有脑外伤及脑血管病3320g。瘀血重,加鸡血藤30g,丹皮15g,土元15g;例,骨科病14例,外科病19例,不明原因5例。病湿邪甚,加防已12g,泽泻12g,益母草15g;偏阴虚,程3个月以内45例
