ovarian cancer(ppt-82)

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1、OVARIANCANCERDiWen,M.D.,Ph.DDefinitionOvariantumorsmayariseatanyage,butarecommonestbetween30and60.1.Ovariantumorsareparticularlyliabletobeortobecomemalignant.2.Intheirearlystagestheyareasymptomaticandpainless.3.Theymaygrowtoalargesizeandtendtoundergomechanicalcomplicationssuchastorsionandperforat

2、ion.OVARIANTUMOURS2003-10-272OvarianCancerDefinitionIndevelopedcountries，womenhavealifetimeriskofdevelopingovariancancerofabout1.4%，whichisslightlygreaterthantheriskofcervicalorendometrialcancers,butwellbelowthe7%averageriskofbreastcancer．CARCINOMAOFTHEOVARY2003-10-273OvarianCancerRiskFactorGenet

3、icfactoraresometimesinvolved、asintheLynchSyndromeoffamilialbreastcolorectalandovariancancer．OvulationinductionwithClomipheneovermorethanyearcarriesal0-foldincreasedriskofovariancancer,Long-termora1contraceptiveusereducestheincidenceofovariancancers．CARCINOMAOFTHEOVARY2003-10-274OvarianCancerIncid

4、enceNearly25%ofallovarianneoplasmaremalignant．Approximately80％ofthemareprimarygrowthsoftheovary、theremainderbeingsecondary，usuallycarcinomata．CARCINOMAOFTHEOVARY2003-10-275OvarianCancerPrimaryCarcinomaoftheOvary80％ofallcasesofprimarycarcinomaoftheovaryariseinserousormucinouscysts.CARCINOMAOFTHEOV

5、ARY2003-10-276OvarianCancerSolidCarcinomaoftheOvaryThisaccountsfor10%ofprimarycarcinoma.Itisarisecommonlybilateralbutonetumorisusuallylargerthantheother.Theovarianshapeisretainedforatimeandthereisawell-markedpediclebutsoonthetumorsbecomefixed.Secondarydepositsoccurintheomentumandascitesdevelops.C

6、ARCINOMAOFTHEOVARY2003-10-277OvarianCancerSymptomsduetoSizeLackofanyspecificsymptoms,ovariantumorsareoftenlargebythetimethedoctorisconsulted.CLINICALFEATURESOFOVARIANTUMOURS2003-10-278OvarianCancerMenstrualfunctionisseldomupset,andanyirregularityisattributedtothepatient’s‘timeoflife’.2003-10-279O

7、varianCancerShemayhavenoticedthatherclothesaregettingtightantattributedthistoweightgainor,iftheabdominalswellinghascoincidedwithamenorrheashemaybelieveherselftobepregnant.2003-10-2710OvarianCancerPressureSymptomsThesea