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1、SURGICALAPPROACHFORTREATMENTOFEPIDERMOIDANALCARCINOMAARMANDF.CORTESE,MD*Theincidenceofmalignancyoftheanusisrarewhencomparedtocolorectalcancer.AtTheNewYorkHospital-Come11MedicalCenter,43patientswithanalcancerwereseensince1932.Five-yearsurvivalforpatientstreatedbylocalexcision,abdominal-perinealresect
2、ion,andabdominalperinealresectionwithassociatedinguinofemoralgroinnodedissectionwas4396,6696,and3396,respectively.Therapyshouldbeguidedbylocation,size,anddepthofthelocallesion,aswellasclinicalnodestatus.Ingeneral,localexcisionshouldbereservedforthemostminutelesion.Groindissectionshouldbecarriedoutwh
3、ennodesareclinicallydiseased.Cancer36:1869-1875,1975.PIDERMOIDMALIGNANCIESOFTHEANALRE-PriorbenignanaldisorderswereidentifiedEgionareinfrequentwhencomparedtoinsomepatients,includinghemorrhoidsintheincidenceofcancersofthedistalcolorec-10,condylomataaccuminatain2,andanaltum.Epiderinoidlesionsaccountedf
4、or3.9%fissurein1.Therewasnootherpastbenignof6000patientswithmalignancyofthedistalmedicalorfamilyhistorypertinenttothe18cmoftheintestinereviewedatMemorialpresentillnessinanypatient.HospitallTand1%ofalllargebowelcancerFourpatientshadpriorcancers;oneeachattheMayoClinic.12AtTheNewYorkHos-ofthebreast,sig
5、moidcolon,brain,andthy-pital-CornellMedicalCenter,the43patientsroid.Nopatienthadaprevioushistoryofwithanalcanceraccountedfor2.6%oftheradiationexposuretotherectalorperianalpatientswithcolorectalcancerseensince1932.regions.Similarlylowincidencefigureshavebeenre-Thedurationofdiscretesignsofsymptomsport
6、edelsewhere.15~21variedfrom7yearsto0intervalinthetwopatientsinwhomasilentanallesionwasdis-PATIENTScoveredonphysicalexamination.Thebulkofpatientsweresymptomaticforlessthan1Forty-threepatientswithmalignancyoftheyearbeforerecognitionofthecancer.TheanalcanalatTheNewYorkHospitalvariedmostcommonfirstmanif
7、estationwasanorec-inagefrom33to90years,withanaverageoftalbleeding:thesecondmostcommonsign61years.Allthepatientswerewhite.wasthefeelingofaperianallump.Pain,Thehistopathologicdiagnosisfor38ofchangeinbow