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1、MINIREVIEWBeyondthefringe:whensciencemovesfrominnovativetononsenseSimonSilverDepartmentofMicrobiologyandImmunology,UniversityofIllinois,Chicago,IL,USACorrespondence:SimonSilver,DepartmentAbstractofMicrobiologyandImmunology,UniversityofIllinois,Chicago,IL60
2、612,USA.MicrobiologyhasexperiencedexamplesofhighlyproductiveresearcherswhoTel.:+13129969608;havegonebeyondjustinterpretingtheirexperimentalresultswithhypothesesfax:+13129966415;andpublishednonsensethatwasreadilyrecognizedassuchbyreaders.e-mail:simon@uic.ed
3、uAlthoughthemostdiscussedcasesofthispathologycomefromphysics,studiesofsingle-celledmicroorganisms,virology,andimmunologyhaveprovidedReceived4August2013;revised5manyexamples.Fivecasesaredescribedherealongwithsomegeneralizations.September2013;accepted13Septe
4、mberThesearetheLamarckianinheritanceofacquiredcharacteristicsreportedby2013.Finalversionpublishedonline21October2013.distinguishedandexperiencedresearchers,vectorlessDNAtransferandincor-porationofbacterialDNAintochromosomesofplantsyearsbeforevectorcon-DOI:
5、10.1111/1574-6968.12289structionofgeneticallymodifiedplantswasinvented,waterwithmemoryofimmunoglobulinIgE,anewelectromagneticradiationmethodforidentifyingEditor:JeffColebacterialandviralpathogensbythediscovererofhumanimmunodeficiencyvirus,andtheclaimofisolat
6、ionofanewbacterialisolatewitharsenicreplac-KeywordsingphosphorusinDNA.Theseexamplesrepresentverydissimilarareas,andLamarckiangenetics;waterwithmemory;theonlycommonfactorishubrisonthepartofexperiencedresearchers.Sec-microbialpathogenicity;GMOplants;ondarily
7、,failureofpeerreviewsometimeshappens,andjournaleditorsdonotarsenicinDNA.stepin,sometimesevenwhenalertedbeforepublication.Thesefailuresofthepublishingprocessteachusthatunnecessarymistakesoccurandshouldwarnusalltowatchourownenthusiasms.regardtoflyingsaucersan
8、dclaimsofgovernmentalThegeneralpicturecover-upofbeyondthefringephysicalscience.Friedlander’sThisisacommentaryonthepublishingofscience,(1995)bookistitled‘Atthefringe….’,sowemoveherebeyondthefringefromwhatisrec
