Recent Advances in the Asymmetric Nozaki–Hiyama–Kishi Reaction

《Recent Advances in the Asymmetric Nozaki–Hiyama–Kishi Reaction》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、SYNTHESIS0039-78811437-210X©GeorgThiemeVerlagStuttgart·NewYork2016,48,A–LAshortreviewSynthesisQ.Tian,G.ZhangShortReviewRecentAdvancesintheAsymmetricNozaki–Hiyama–KishiReactionXQingshanTianBrBrBrXXIR1GuozhuZhang*OX=Br,I,OTfStateKeyLaboratoryofOrganometallicChemistry,S

2、hanghaiInstituteofOrganicChemistry,ChineseOOAcademyofSciences,345LinglingRoad,Shanghaior2000032,P.R.ofChinaRRR'Cr(II)/LnOHOHOHOHOHOHR1RRRRRROHReceived:18.05.2016Acceptedafterrevision:01.07.2016Publishedonline:24.08.2016DOI:10.1055/s-0036-1589457;ArtID:ss-2016-h0362-s

3、rAbstractThisreviewwillsurveyrecentdevelopmentsintheareaofthecatalyticasymmetricNozaki–Hiyama–Kishireaction.Thecontentwillbeclassifiedaccordingtoreactiontypeasfollows:asymmetrical-lylation,asymmetricpropargylation,asymmetricalkynylation,asym-metricvinylation,andasymm

4、etricalkylation.1IntroductionGuozhuZhang(left)receivedhisBachelor’sandMaster’sdegreesin2AsymmetricAllylationorganicchemistryfromNankaiUniversityin2000and2003underthe3AsymmetricPropargylationandAsymmetricHomoallenylationguidanceofProfessorJinpeiCheng.Hespentthreeyears

5、workingin4AsymmetricAlkynylationWuxiPharmatechatShanghaiasagroupleader.Hethenmovedtothe5AsymmetricVinylationandArylationUSAandobtainedhisPh.D.inorganicchemistryfromtheUniversityof6AsymmetricAlkylationCalifornia,SantaBarbarain2011underthesupervisionofProfessor7Intramo

6、lecularNozaki–Hiyama–KishiReactionDownloadedby:Cornell.Copyrightedmaterial.LimingZhang.HethenjoinedProfessorYoshitoKishi’slabattheDe-8ConclusionandPerspectivespartmentofChemistryandChemicalBiology,HarvardUniversitytostudyasymmetricbimetalliccatalysis.HejoinedtheShang

7、haiInstituteKeywordsasymmetriccatalysis,chromium,NHKreaction,alde-ofOrganicChemistry,ChineseAcademyofSciencesasaresearchpro-hydes,C–CbondformationfessorinNov.2013tostudymultimetal-catalyzedenantioselectivecarbon–carbonbond-formationreactions.QingshanTian(right)wasbor

8、nin1978inShandongprovinceofChina.1IntroductionHestudiedchemistryatTongjiUniversityandreceivedhisPh.D.degreein2015.Since2015,hehasbe