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1、ViewArticleOnlineViewJournalAnalystAcceptedManuscriptThisarticlecanbecitedbeforepagenumbershavebeenissued,todothispleaseuse:N.Duan,S.Wu,S.Dai,H.Gu,L.Hao,H.YeandZ.Wang,Analyst,2016,DOI:10.1039/C6AN00952B.ThisisanAcceptedManuscript,whichhasbeenthroughtheRoyalSocietyofChemi
2、strypeerreviewprocessandhasbeenacceptedforpublication.AcceptedManuscriptsarepublishedonlineshortlyafteracceptance,beforetechnicalediting,formattingandproofreading.Usingthisfreeservice,authorscanmaketheirresultsavailabletothecommunity,incitableform,beforewepublishtheedite
3、darticle.WewillreplacethisAcceptedManuscriptwiththeeditedandformattedAdvanceArticleassoonasitisavailable.YoucanfindmoreinformationaboutAcceptedManuscriptsintheInformationforAuthors.Pleasenotethattechnicaleditingmayintroduceminorchangestothetextand/orgraphics,whichmayalte
4、rcontent.Thejournal’sstandardTerms&ConditionsandtheEthicalguidelinesstillapply.InnoeventshalltheRoyalSocietyofChemistrybeheldresponsibleforanyerrorsoromissionsinthisAcceptedManuscriptoranyconsequencesarisingfromtheuseofanyinformationitcontains.www.rsc.org/analystPage1of2
5、0PleasedonotadjustmarginsAnalystViewArticleOnlineDOI:10.1039/C6AN00952B1234JournalName567ARTICLE891011Advancesinaptasensorsforthedetectionoffoodcontaminants1213NuoDuan†,ShijiaWu†,ShaoliangDai,HuajieGu,LilingHao,HuaYe,ZhoupingWang*14Received00thJanuary20xx,Accepted00thJan
6、uary20xxFoodsafetyisaglobalhealthobjective,andfoodbornediseasesrepresentamajorcrisisinhealth.Techniquesthatare1516DOI:10.1039/x0xx00000xsimpleandsuitableforfastscreeningtodetectandidentifypathogenicfactorsinthefoodchainarevitaltoensurefood17safety.Atpresent,avarietyofana
7、lyticalmethodshavebeenreportedforthedetectionofpathogenicagents.Whereaswww.rsc.org/18sensitivityofdetectionandquantificationarestillimportantchallenges,weexpectmajoradvancesfromnewassay19formatsandsyntheticbio-recognitionelements,suchasaptamers.Owingtothespecificfoldingc
8、apabilityofaptamersin20thepresenceofanalyte,aptasensorshavesubstantiallyandsuccessfullybeenexploitedfor
