资源描述：
《丁苯酞联合高压氧疗法对血管性痴呆患者的疗效和安全性分析》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。
1、我院未开展胰岛素样生长因子一1，细胞间粘附因子一1，血浆转化生长因子一B,氧化物歧化酶水平，请做改动。我院开展血流变，同型半胱氨酸。丁苯酞联合高压氧疗法对血管性痴呆患者的疗效和安全性分析【摘要】目的探讨丁苯酞联合高压氧治疗血管性痴呆的近期疗效和安全性，为临床治疗提供参考依据。方法选择我院2013年1月至2015年12月收治的100例血管性痴呆患者作为研究对象，根据随机数字表法分为观察组和对照组，每组各50例。在常规治疗的基础上对照组给予高压氧治疗，在对照组治疗的基础上观察组给予丁苯酞治疗。治疗3个月后比较两组患者的临床疗效、简易精神状态检查量表（MMSE）、临床痴呆评
2、定量表（CDR）、日常生活活动量表（ADL）评分及血液流变学。结果观察组临床疗效显著优于对照组，差异有统计学意义（Z=2.203，P＜0.05）；治疗3个月后，观察组MMSE、ADL评分均高于对照组，CDR评分低于对照组（P＜0.05）；观察组血浆黏度、全血中切黏度、红细胞聚集指数、全血低切黏度及全血高切黏度均明显低于对照组（P＜0.05）。结论丁苯酞联合高压氧疗法治疗血管性痴呆疗效显著，明显改善了患者近期生活能力及认知功能，且无严重不良反应发生，值得临床重视。【关键词】血管性痴呆；丁苯酞；高压氧疗法；临床疗效；安全性Efficacyandsafetyofbutylp
3、hthalidecombinedwithhyperbaricoxygentherapyonvasculardementia【Abstract】ObjectiveToinvestigatetheshort-termeffectsandsafetyofbutylphthalidecombinedwithhyperbaricoxygentherapyonvasculardementia,toprovidereferenceforclinicaltreatment.Methods100casesofvasculardementiainourhospitalfromJanuar
4、y2013toDecember2015wereselectedasresearchsubjects,Accordingtotherandomnumbertablemethodweredividedintoobservationgroupandcontrolgroup,eachgroupof50cases.Onthebasisofroutinetreatment,thecontrolgroupwastreatedwithhyperbaricoxygen,onthebasisofthecontrolgrouptreatment,theobservationgroupwas
5、treatedwithbutylphthalide.After3monthsoftreatment,theclinicalcurativeeffect,theminimentalstateexaminationtable(MMSE)andClinicalDementiaRatingScale(CDR),activitiesofdailylivingscale(ADL)scoreandbloodrheologywerecomparedbetweenthetwogroups.ResultsTheclinicalefficacyoftheobservationgroupwa
6、ssignificantlybetterthanthecontrolgroup,thedifferencewasstatisticallysignificant(Z=2.203,P<0.05);After3monthsoftreatment,TheMMSE,ADLscoresintheobservationgroupwerehigherthanthecontrolgroup,theCDRscorewaslowerthanthecontrolgroup(P<0.05);Theplasmaviscosity,wholebloodviscosity,erythrocytea
7、ggregationindex,wholebloodlowshearviscosity,wholebloodviscosityinobservegroupweresignificantlylowerthanthoseofthecontrolgroup(P<0.05).ConclusionButylphthalidecombinedwithhyperbaricoxygeninthetreatmentofvasculardementiaeffectissignificant,cansignificantlyimprovethepatientswithre
