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1、Asthmaintheelderly:Currentunderstandingandfutureresearchneeds—areportofaNationalInstituteonAging(NIA)workshopabcdNicolaA.Hanania,MD,MS,(Co-chair),*MonroeJ.King,DO,(Chair),*SidneyS.Braman,MD,CarolSaltoun,MD,efghiRobertA.Wise,MD,PaulEnright,MD,AnnR.Falsey,MD,SameerK.Mathur,MD,PhD,JoeW.R
2、amsdell,MD,jklmnLindaRogers,MD,DavidA.Stempel,MD,JohnJ.Lima,PharmD,JamesE.Fish,MD,SandraR.Wilson,PhD,eopqCynthiaBoyd,MD,MPH,KushangV.Patel,PhD,CharlesG.Irvin,PhD,BarbaraP.Yawn,MD,MSc,ristEthanA.Halm,MD,MPH,StephenI.Wasserman,MD,MarkF.Sands,MD,WilliamB.Ershler,MD,andbDennisK.Ledford,MD
3、,fortheAsthmaintheElderlyworkshopparticipantsàHoustonandDallas,Tex,TampaandJacksonville,Fla,Providence,RI,Chicago,Ill,Baltimore,Bethesda,andGaithersburg,Md,Tucson,Ariz,NewYork,Rochester,andBuffalo,NY,Madison,Wis,SanDiegoandPaloAlto,Calif,Bellevue,Wash,Gladwyne,Pa,Burlington,Vt,andRoch
4、ester,MinnAsthmaintheelderlyisunderdiagnosedandundertreated,andKeywords:Aging,airway,allergy,asthma,elderly,immunemecha-thereisapaucityofknowledgeonthesubject.TheNationalnisms,immunosenescenceInstituteonAgingconvenedthisworkshoptoidentifywhatisknownandwhatgapsinknowledgeremainandsugge
5、stresearchdirectionsneededtoimprovetheunderstandingandTheproportionofpersonsolderthan65yearsintheUnitedcareofasthmaintheelderly.AsthmapresentingatanadvancedStatesiscurrentlyabout13%butisprojectedtogrowfromaboutageoftenhassimilarclinicalandphysiologicconsequencesas40millionin2005tomore
6、than86millionby2050,accountingseenwithyoungerpatients,butcomorbidillnessesandthefor25%ofthepopulation.Theagegroupwiththelargestgrowthpsychosocialeffectsofagingmightaffectthediagnosis,clinicalwillbethoseolderthan85years,whichisestimatedtobemore1,2presentation,andcareofasthmainthispopul
7、ation.Atleast2than1millionby2050.In2004,theUSprevalenceofasthmaphenotypesexistamongelderlypatientswithasthma;thosewithforthose65yearsorolderwas7%,with1,088,000reportingan3longstandingasthmahavemoresevereairflowlimitationandasthmaattackintheprevious12months.Olderasthmaticpa-4,5lesscompl
8、etere
