Micro- and Nano-Transport of Biomolecules

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1、Micro-andNano-TransportofBiomoleculesDavidBakewellDownloadfreebooksatDavidBakewellMicro-andNano-TransportofBiomolecules2DownloadfreeeBooksatbookboon.comMicro-andNano-TransportofBiomolecules©2009DavidBakewell&VentusPublishingApSISBN978-87-7681-513-43DownloadfreeeBooksatbookb

2、oon.comMicro-andNano-TransportofBiomoleculesContentsContentsPreface71Introduction81.1Motivation:biomoleculesinscientificcontext81.2Lengthscaleoftransport101.3Biomoleculetransportexample:engineeredmicrodevices111.4Structureofthise-book132Biomoleculesandtheirelectricalproperti

3、es142.1Biomoleculesincells142.2Biomolecules:structureandfunction162.2.1Nucleicacids162.2.2Proteins202.2.3Carbohydrates212.2.4Lipids222.3Biomolecules:electricalproperties222.3.1Polyelectrolytes222.3.2DNAcanbemodeledaswormlikechain360°242.3.3Biomoleculesandbioparticles252.3.4

4、Electricaldoublelayer252.3.5Introductiontodielectricpolarizationthinking.272.3.6Polarisationparameters:abriefview282.3.7Measurementofbiomoleculepolarisationparameters292.4Concludingremarks30360°thinking.360°thinking.Discoverthetruthatwww.deloitte.ca/careersDiscoverthetrutha

5、twww.deloitte.ca/careers©Deloitte&ToucheLLPandaffiliatedentities.Discoverthetruthatwww.deloitte.ca/careers©Deloitte&ToucheLLPandaffiliatedentities.©Deloitte&ToucheLLPandaffiliatedentities.4Discoverthetruthatwww.deloitte.ca/careersClickontheadtoreadmoreDownloadfreeeBooksatbo

6、okboon.com©Deloitte&ToucheLLPandaffiliatedentities.Micro-andNano-TransportofBiomoleculesContents3Movingbiomoleculesusingelectricfields313.1Electrophoresis313.2Dielectrophoresis(DEP)323.2.1PolarisationandDEPbiomoleculetransport363.2.2Maxwell-Wagnerinterfacialpolarisation373.2

7、.3Maxwell-Wagnerinterfacialpolarisationforbioparticles383.2.4Maxwell-WagnerpolarisationforDNA413.2.5Counterionfluctuationpolarisation433.2.6Counterionfluctuationpolarisationforbioparticles433.2.7CounterionfluctuationpolarisationforDNA463.2.8Otherpolarisationmechanisms513.3Micr

8、o-environmentsforbiomoleculetransport513.4Concludingremarks524Basicmicro-andnano-t