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1、DigestiveEndoscopy2013;25:526–534doi:10.1111/den.12032OriginalArticleEndoscopicdiagnosisofgastricintestinalmetaplasia:Aprospectivemulticenterstudy1112NobuhiroFukuta,KazunoriIda,TakahiroKato,NoriyaUedo,345TakashiAndo,HidenobuWatanabe,TakuroShimboand*StudyGroupf
2、orInvestigatingEndoscopicDiagnosisofGastricIntestinalMetaplasia12DepartmentofGastroenterology,MurakamiMemorialHospital,AsahiUniversity,Gifu,Departmentof3Gastroenterology,OsakaMedicalCenterforCancerandCardiovascularDiseases,Osaka,Departmentof4Gastroenterology,S
3、ocialInsuranceKyotoHospital,Kyoto,DepartmentofPathology,NiigataUniversity,Niigata5andDepartmentofClinicalResearchandInformatics,InternationalClinicalResearchCenter,ResearchInstitute,InstituteMedicalCenterofJapan,Tokyo,JapanBackground:Intestinalmetaplasia(IM)of
4、thegastricmucosacurve(ROC/AUC)ofconventionalandICmethodsforthedetectionhaslongattractedattentionasapremalignantlesioninvolvedinofIMinthegastricantrumshowedthatdiagnosticperformanceofgastriccarcinogenesis.However,endoscopicdiagnosisofIMhastheconventionalmethodw
5、ashigher,butnotsignificantly,thanremainedunclearforalongtime.Inrecentyears,themethylenethatoftheICmethod.Sensitivity,specificityandROC/AUCofbluestainingtechniqueandnarrow-bandimaging(NBI)magnify-conventionalandICmethodsforthedetectionofIMinthegastricingendoscopy
6、havefacilitatedclinicaldiagnosisofIM,althoughbodyshowedthattheICmethodyieldedbetter(butnotsignifi-thesemethodshavesomeproblemsduetotheircomplexity.cantlybetter)resultsthantheconventionalmethod.SimplemethodsfordiagnosisofIMusingconventionalendos-Conclusion:Thedi
7、agnosticperformanceoftheconventionalcopyandtheindigocarminecontrast(IC)methodarenecessary.methoddidnotsignificantlydifferfromthatoftheICmethod.APatientsandMethods:Thisstudywasamulticenter,pro-villousappearance,whitishmucosa,androughmucosalsurface,spective,rando
8、mized,comparativestudyinvolving10facilities.asobservedbybothmethods,andareaegastricaepattern,asTheappearanceofIMwasexaminedusingconventionalandICobservedbytheICmethod,wereusefulind
