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1、CentersforDiseaseControlandPreventionEpidemiologyProgramOfficeCaseStudiesinAppliedEpidemiologyNo.711-903Texarkana—EpidemicMeaslesinaDividedCityStudent'sGuideLearningObjectivesAftercompletingthiscasestudy,theparticipantshouldbeableto:GDiscusstheadvantagesanddisadvantagesofusingasensitiveand
2、/orspecificcasedefinitioninanepidemicinvestigation;GCalculatevaccineefficacyanddiscussitsinterpretation;andGDiscusstheadvantagesandlimitationsofselectingaspecificageastherecommendedtargetdateforadministeringvaccinations.ThiscasestudyisbasedonaninvestigationbyPhilipLandrigan,EIS‘70.Theinves
3、tigationisdescribedin:LandriganPJ.Epidemicmeaslesinadividedcity.JAMA1972;221:567-570.ThiscasestudywasoriginaldevelopedbyPhilipLandrigan,LyleConradandJohnWittein1971.ThecurrentversionwasupdatedbyRichardDickerin2001and2003.U.S.DEPARTMENTOFHEALTHANDHUMANSERVICESPublicHealthServiceCDC-EIS,2003
4、:Texarkana:MeaslesinaDividedCity(711-903)–Student’sGuidePage2PARTIOnTuesday,November3,1970,theCenterforTexarkana,Texas(BowieCounty),hadaDiseaseControl(CDC)inAtlantareceivedthepopulationof29,393inthe1960census;theweeklytelegramofsurveillancedatafromthepopulationhadbeenstableduringthe1960s.T
5、exasStateHealthDepartment.ThetelegramTexarkana,Arkansas(MillerCounty),hadareported319casesofmeaslesinthestate1960populationof21,088.duringthepreviousweek.Incontrast,Texashadreportedanaverageof26casesperweekAlthoughTexarkanaisdividedbythestateline,duringthepreviousfourweeks.Infollow-upitisa
6、singletowneconomicallyandsocially.telephonecalls,CDClearnedfromStatehealthPersonsofallagesonbothsidesoftownhaveofficialsthat295casesofmeasleshadbeenfrequentcontact.Churches,physicians,offices,diagnosedinthecityofTexarkana,including25movietheatres,andstoresdrawpeoplefrominchildrenreportedto
7、havebeenpreviouslyboththeArkansasandTexassidesoftown.immunized.PeoplecrossthestatelinetoattendsocialfunctionssuchasfootballgamesandschoolAninvitationtoinvestigatethesituationwasdances.ManyfamilieshavefriendsandextendedtotheCDConNovember4,1970.Anrelativeswhovis
