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1、DOI:10.13455/j.cnki.cjcor.2004.03.025·250·中国肿瘤临床与康复2004年6月第11卷第3期ChinJClinOncolRehabil,June2004,Vol11,No.3·临床应用·胸骨肿瘤的初步治疗经验黄进丰张德超(中国医学科学院协和医科大学肿瘤医院胸外科,北京100021)【摘要】目的探讨胸骨肿瘤诊断和治疗的临床特点。方法回顾性总结中国医学科学院肿瘤医院胸外科1967年3月～2001年8月治疗的胸骨肿瘤12例,均经病理科复核阅片。结果软骨肉瘤5例,2例分别于术后18年、25年非肿瘤死亡,3例术后分别生
2、存62个月、11个月、12个月后失访;骨肉瘤1例,经术前、术后化疗,已无瘤生存53个月;恶性纤维组织细胞瘤1例,术后无瘤生存17个月后失访;骨巨细胞瘤1例,术后无瘤生存66个月;淋巴瘤1例,术后生存17个月;脂肪肉瘤1例,未手术,生存28个月后失访;转移性腺癌2例,其中放化疗1例生存7个月,手术1例生存27个月。结论治疗胸骨肿瘤术前必须先明确病理类型,软骨肉瘤、恶性纤维组织细胞瘤宜选择手术切除;骨肉瘤应选择化疗+手术;而浆细胞瘤、淋巴瘤、Ewing肉瘤可采用非手术治疗,若手术应严格筛选。胸壁重建可应用人工合成物和转移性肌皮瓣。【关键词】胸骨肿瘤;
3、治疗【中图分类号】R738.1;R730.5【文献标识码】A【文章编号】1005-8664(2004)03-0250-03Treatmentofsternaltumorsand12casesreportHUANGJin-feng,ZHANGDe-chao(Departmentofthoracicsurgery,CancerInstitute,ChineseAcademyofMedicalScience,PekingUnionMedicalCol-lege,Beijing100021,China)【Abstract】ObjectiveToexami
4、netheefficacyandinvestigatetheadvanceinthetreatment,sternaltu-mors.MethodsFromMarch1967toAugust2001,12patientsunderwentsurgicaltreatment,chemotherapyorra-diotherapyforpathologicallyconfirmedsternaltumorsatourCancerInstitute(Hospital),CAMS.ResultsOffivepatientswithchondrosarco
5、matreatedbyresection,twodiednotoftumor,andhadbeenalivefor18yearsand25years,respectively;threehadbeenalivefor62months,11monthsand12months,respectively,beforetheywerelosttofollow-up.Apatientwithosteosarcomaremainsaliveandwell53monthsafteroperationandadjuvantchemotherapy.Onepati
6、entwithalignantfibroushistiocytomahadbeenalivefor17monthsafterresection,beforebeinglosttofollow-up.Apatientwithbonegiantcelltumorsurvivedfor66monthsfreeoftumorafteroperation.Onepatientwithlymphomawasalivefor11monthsafterresection.Apatientwithliposarcomatreatednonsurgicallyrec
7、eivedradiotherapyandchemotherapy,andwaslosttofollow-upat28months.Twopatientshadsternalmetastasisofadenocarcinomaofunknownorigin.Oneofthemtreatedwithradiotherapyandchemotherapysurvivedfor7monthsandtheothertreatedsurgicallysurvivedfor27months.ConclusionsItisimportanttoidentifyp
8、rimarysternaltumorspathologicallybeforetreatment,becausethesurvivalo
