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1、ImageCopyrIght:THOMSONREUTERSTHEYEAR’SNEWDRUGS&BIOLOGICS-2009Comprehensiveannualreviewofthe51newmedicinesandvaccinesthatreachedtheirfirstmarketsin2009,withalookatthenewtrendsandnovelmechanismsofaction,aswellaspredictionsforthenewdrugsandbiologicsthatwillmakeittomarketin2010.This
2、reportispublishedannuallyintheThomsonReuters’journalDrugNews&PerspectivesanddrawsoninsightsandinformationfromThomsonReutersIntegritySM.ImageCopyrIght:iSTOCKPHOTOTHOMSONREUTERSINTEGRITYSMESSENTIALKNOWLEDGETOEMPOWERYOURDRUGDISCOVERYANDDEVELOPMENTThomsonReutersIntegritySMintegrates
3、biology,chemistryandpharmacologydataonmorethan315,000compoundswithdemonstratedbiologicalactivity,plustensofthousandsofsynthesisintermediates,andover135,000patentfamilyrecords.Updatedeveryday,itswealthofinformationformsacomplete,flexibleresourcethatcandriveknowledgecreation,targe
4、tmission-criticalmilestones,andsupportfaster,strategicdecisionsearlierinthediscoverypipeline.Designed,populated,refinedandsupportedentirelybypharmaceuticalscientistsandexperts,Integrityprovidesauniqueknowledgesolutiondesignedtoempoweryourdiscoveryactivitiesrightwhereyouneeditmos
5、t—atthebench.Tofindoutmore,goto:go.thomsonreuters.com/integrityDrugNewsPerspect23(1),January/February2010DRUGLINEThisyear,51newproducts,includingTHEYEAR'SNEWDRUGS&newchemicalentitiesBIOLOGICS—2009andbiologicsfortherapeuticuse,reachedtheirfirstmarkets.influenza.TheU.S.wasagainthe
6、mostactivebyAnnI.Graul,LisaSorbera,singlemarketfornewproducts,withatotalofSUMMARYPatriciaPina,MontseTell,24newlaunchesin2009,constitutingThisannualarticlepresentsnewdrugsElisabetCruces,EsmeraldaRosa,almost50%ofthetotalofnewintroductionsandbiologicsthatwerelaunchedorMarkStringer,
7、RosaCastañerfortheyear.TheEuropeanUnionfollowedapprovedforthefirsttimeduringtheandLauraRevelclosebehind,with18newlaunches(Fig.1).previousyear.In2009,51newmedi-cinesandvaccinesreachedtheirfirstTheinformationinthisreviewwascompiledNowinits22ndedition,theannualseriesmarkets.Lineext
8、ensions(newindica-fromcompanycommunicationsandt
