资源描述：
《DARPA's Big Mechanism programDARPA的大机制计划》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。
1、PhysicalBiologyPAPER•OPENACCESSRelatedcontent-Modelingfor(physical)biologists:anDARPA'sBigMechanismprogramintroductiontotherule-basedapproachLilyAChylek,LeonardAHarris,JamesRFaederetal.Tocitethisarticle:PaulRCohen2015Phys.Biol.12045008-Fromphysicstopharmacology?RichardJAllenandTimothyCElston-State
2、--timespectrumofsignaltransductionlogicmodelsViewthearticleonlineforupdatesandenhancements.AidanMacNamara,CamilleTerfve,DavidHenriquesetal.Recentcitations-Emergingwhole-cellmodelingprinciplesandmethodsArthurPGoldbergetal-DynamicInfluenceNetworksforRule-BasedModelsAngusG.Forbesetal-LitPathExplorer:
3、aconfidence-basedvisualtextanalyticstoolforexploringliterature-enrichedpathwaymodelsAxelJSotoetalThiscontentwasdownloadedfromIPaddress60.186.211.6on06/08/2018at03:13Phys.Biol.12(2015)045008doi:10.1088/1478-3975/12/4/045008PAPERDARPAʼsBigMechanismprogramOPENACCESSPaulRCohenRECEIVEDDefenseAdvancedRe
4、searchProjectsAgency(DARPA)7November2014E-mail:paulrcohen@gmail.comREVISED21April2015Keywords:signalingpathways,machinereading,biocuration,informationextraction,artificialintelligence,modeling,systemsbiologyACCEPTEDFORPUBLICATION5May2015PUBLISHED15July2015AbstractReductionistscienceproducescausalmo
5、delsofsmallfragmentsofcomplicatedsystems.CausalContentfromthisworkmodelsofentiresystemscanbehardtoconstructbecausewhatisknownofthemisdistributedacrossmaybeusedunderthetermsoftheCreativeavastamountofliterature.TheBigMechanismprogramaimstohavemachinesreadtheliteratureCommonsAttribution3.0licence.and
6、assemblethecausalfragmentsfoundinindividualpapersintohugecausalmodels,automatically.AnyfurtherdistributionofThecurrentdomainoftheprogramiscellsignallingassociatedwithRas-drivencancers.thisworkmustmaintainattributiontotheauthor(s)andthetitleofthework,journalcitationWhenitcomestocomplicatedsystemssu
7、chasthe[2,8,41,52,54,55,63]);whileitdevelopsrepresenta-andDOI.climate,andeconomic,ecologicalandbiologicaltionsandinferencemethodsformechanisticbiologi-systems,ourinfluencerunsaheadofourunderstand-calmodels,methods
