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1、SOGCCLINICALPRACTICEGUIDELINESOGCClinicalPracticeGuidelineNo.249,October2010AsymptomaticEndometrialThickeningAbstractThisClinicalPracticeGuidelinehasbeenpreparedbytheClinicalObjective:ToformulateclinicalrecommendationsfortheassessmentPracticeGynaecologyCommitteeandapprovedbythe
2、ExecutiveofendometrialthickeningwhenitisfoundonultrasoundinaandCounciloftheSocietyofObstetriciansandGynaecologistsofpostmenopausalpatientwithoutbleeding.Canada.Outcomes:EnsurethatwomenwithasymptomaticthickeningandPRINCIPALAUTHORendometrialpolypsfoundonultrasoundaremanagedapprop
3、riately.WendyWolfman,MD,TorontoONEvidence:PublishedliteraturewasretrievedthroughsearchesofCLINICALPRACTICEGYNAECOLOGYCOMMITTEEEnglishlanguagearticlesfromtheEMBASE,Cochrane,andPubMedNicholasLeyland,MD(Chair),NorthYorkONdatabasesforrelevantpeer-reviewedarticlesdatingfrom1970to200
4、9,usingappropriatecontrolledvocabulary(e.g.,“asymptomaticWendyWolfman,MD,TorontoONendometrialthickness,”“endometrialcancer,”“postmenopausalMarkHeywood,MD,VancouverBCbleeding,”“transvaginalultrasonography,”“endometrialbiopsy”and“endometrialpolyp”).Resultswererestrictedtosystemat
5、icSukhbirS.Singh,MD,OttawaONreviews,randomizedcontroltrials/controlledclinicaltrials,andDavidAllanRittenberg,MD,HalifaxNSobservationalstudies.SearcheswereupdatedonaregularbasisRenéeSoucy,MD,ChandlerQCandincorporatedintheguidelinetoApril2010.Grey(unpublished)literaturewasidentif
6、iedthroughsearchingthewebsitesofhealthCatherineAllaire,MD,VancouverBCtechnologyassessmentandhealthtechnologyassessment-relatedAlaaAwadalla,MD,WinnipegMBagencies,clinicalpracticeguidelinecollections,clinicaltrialregistries,andnationalandinternationalmedicalspecialtysocieties.Car
7、olynBest,MD,TorontoONValues:ThelevelofevidencewasdeterminedaccordingtothecriteriaSheilaDunn,MD,TorontoONestablishedbytheCanadianTaskForceonPreventativeHealthCareNathalieLeroux,MD,MontrealQC(Table).Recommendationsarerankedaccordingtothismethod.FrankPotestio,MD,ThunderBay,ONBenef
8、its,harms,andcosts:ItisanticipatedthattheadoptionofVyt