抗血栓药物在内镜操作时的管理

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1、Management【管理】ofantithrombotic【抗血栓形成的】agents【药剂】forendoscopic【内窥镜检查的】procedures【程序、操作、步骤、过程】ThisisoneofaseriesofstatementsdiscussingtheuseofGIendoscopy【胃肠内镜检查】incommonclinicalsituations.TheStandards【标准】ofPracticeCommitteeoftheAmericanSocietyforGastrointestinalEndoscopy(ASGE)【美国胃肠镜协会】prepare

2、dthistext.Thisguideline【指导原则】combinesandupdates2previously【以前】issuedguidelines,‘‘Guidelineonthemanagementofantithromboticandantiplatelettherapy【抗血小板治疗】forendoscopicprocedures’’1and‘‘ASGEguideline:themanagementoflow-molecular-weightheparin【低分子肝素】andnonaspirin【非阿司匹林】antiplateletagentsforendos

3、copicprocedures.’’2Topreparethisguideline,asearchofthemedicalliteraturewasperformedusingPubMed【免费搜索引擎，提供生物医学方面的论文搜索以及摘要】.Studiesorreportsthatdescribedfewerthan【少于】10patientswereexcludedfromanalysisifmultipleserieswithmorethan10patientsaddressingthesameissuewereavailable.Additional【额外的】refer

4、ences【参考】wereobtained【获得】fromthebibliographies【文献】oftheidentified【确认】articlesandfromrecommendations【推荐、建议】ofexpertconsultants【专家顾问】.Guidelinesforappropriate【合适的】useofendoscopyarebasedonacriticalreview【批评性审查】oftheavailabledataandexpertconsensus【一致同意】atthetimetheguidelinesaredrafted【制定、起草】.Fu

5、rthercontrolledclinicalstudiesmaybeneededtoclarify【使清楚，澄清】aspects【方面】ofthisguideline.Thisguidelinemayberevised【修订、修正】asnecessarytoaccountforchangesintechnology,newdata,orotheraspectsofclinicalpractice.Therecommendations【推荐、建议】arebasedonreviewedstudies【综述研究】andweregradedon【被分级】thestrengthoft

6、hesupportingevidence(Table1).3Thestrengthofindividual【个人的、独特的】recommendationsisbasedonboththeaggregate【总数的、总计的】evidencequalityandanassessment【评估、评价】oftheanticipated【预先的、预期的】benefitsandharms.Weaker【微弱的、无说服力的】recommendationsareindicatedbyphrasessuchas“wesuggest”whereasstrongerrecommendationsa

7、retypicallystatedas“werecommend.”TABLE1.GRADEsystemforratingthequalityofevidenceforguidelinesQualityofevidenceDefinition【定义】SymbolHighqualityFurtherresearchisveryunlikelytochangeourconfidenceintheestimateofeffect++++ModeratequalityFurtherresearchislikely