资源描述：
《一种酚羟基的烃化反应方法》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。
1、wSyntheticCommunications,35:17591764,2005Copyright#Taylor&Francis,Inc.ISSN0039-7911print/1532-2432onlineDOI:10.1081/SCC-200063928RapidandHigh-YieldSynthesisofAryloxyacetatesUnderMicrowaveIrradiationandPhase-TransferCatalysisConditionsTai-BaoWei,HongLiu,Man-LinLi,
2、andYou-MingZhangDepartmentofChemistry,GansuKeyLaboratoryofPolymerMaterials,NorthwestNormalUniversity,Lanzhou,ChinaAbstract:Aseriesofmethylaryloxyacetates(3a3f)havebeensynthesizedbythereactionofsubstitutedphenolwithmethylchloroacetateundertheconditionsofmicrowavei
3、rradiationandphase-transfercatalysis.Bytheoptimizationofthereactionconditions,wedevelopedagoodmethodforthepreparationofmethylaryloxyacetates,whichhavetheadvantagesofhighyields,shortreactiontimes,easeofworkup,andsimpleoperation.Keywords:Methylaryloxyacetates,micro
4、wave,phase-transfercatalystINTRODUCTIONThederivativesofaryloxyaceticacidsconstituteaclassofcompoundsforboth[15][610]biologicalactivityandplantgrowthregulators.Somearefoundto[11]showantituberculoticactivities.Someareusedasapostemergent,[12]selectiveherbicidetocont
5、rolsometerrestrialandaquaticbroad-leavedweeds.Forinstance,severalaryloxyaceticacidsareintheherbicidesmarketwithcommonnamessuchas2,4-D,MCPA,and2,4,5-T.Manyorganicestersofthearyloxyaceticacidsarealsousedasherbicides.Theestersof2,4-D,suchasmethyl,ethyl,propyl,isopro
6、pyl,butyl,amyl,iso-octyl,andReceivedinJapanMarch14,2005AddresscorrespondencetoYou-MingZhang,DepartmentofChemistry,GansuKeyLaboratoryofPolymerMaterials,NorthwestNormalUniversity,Lanzhou,Gansu,730070,China.Fax:þ0869317971216;E-mail:zhangnwnu@126.com17591760T.-B.Wei
7、etal.propyleneglycolbutylesters,haveallbeenusedasselectiveweedkillersinthepresenceofcerealcrops.Aryloxyaceticacidderivativeshavebeenalsoinves-tigatedaschemotherapeuticagentsforloweringtriglycerideslowerthanserum[13]cholesterols.Theyalsopossessfavorablehyperlipida
8、emicactivity.In[14,15]addition,theyareimportantintermediatesinmanyreactions.Byfar,themostcommonsynthesisofaryloxyaceticacidestersisaccom-plishedbyheatingtheaci
