鸦胆子油乳注射液联合博莱霉素治疗原发性肺癌合并癌性胸水临床疗效_黄国平_郑哲

《鸦胆子油乳注射液联合博莱霉素治疗原发性肺癌合并癌性胸水临床疗效_黄国平_郑哲》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。

1、辽宁中医杂志2015年第42卷第3期·533·DOI∶10．13192/j．issn．1000-1719．2015．03．035鸦胆子油乳注射液联合博莱霉素治疗原发性肺癌合并癌性胸水临床疗效黄国平，郑哲(平阳县人民医院呼吸内科，浙江平阳325400)摘要:目的:通过对比研究鸦胆子油乳注射液联合博莱霉素治疗原发性肺癌合并癌性胸水的临床疗效。方法:纳入本院2013年3月—2014年3月原发性肺癌合并癌性胸水的患者72例，随机分为治疗组36例，对照组36例。对照组采用博莱霉素西医方法治疗，治疗组采用鸦胆子油乳注射液联合博莱霉素中西医结

2、合的方法治疗，对患者进行随访3个月，比较两组患者治疗后KPS分值升高率、患者病情缓解率及不良反应率。结果:治疗组患者KPS评分升高率(72.2%)、患者病情缓解率(75%)明显高于对照组(50%、52.8%);而不良反应率(8.3%)却明显低于对照组(13.9%)，各组数据分别对比，有显著差异，P＜0.05，具有统计学意义。结论:鸦胆子油乳注射液联合博莱霉素治疗原发性肺癌合并癌性胸水的疗效优于单纯西医治疗对其的效果，并且具有更高的安全性，值得临床推广，具有重要的临床作用和意义。关键词:鸦胆子油乳注射液;博莱霉素;中西医结合;癌性

3、胸水中图分类号:Ｒ734．2文献标志码:A文章编号:1000-1719(2015)03-0533-02JavanicaOilEmulsionInjectionCombinedwithBleomycininTreatmentofPrimaryLungCancerwithMalignantPleuralEffusionHUANGGuoping，ZHENGZhe(ＲespiratoryDepartmentofInternalMedicine，PingyangCountyPeople＇sHospital，Pingyang325400，Z

4、hejiang，China)Abstract:Objective:TostudytheeffectofJavanicaOilEmulsionInjectioncombinedwithbleomycininthetreatmentofpri-marylungcancerwithmalignantpleuraleffusion．Methods:72patientsofprimarylungcancercomplicatedwithmalignantpleuraleffusioninourhospitalfromMarch2013to

5、March2014wererandomlydividedintotreatmentgroup(36cases)andcontrolgroup(36cases)．ThecontrolgroupwastreatedwithbleomycinandthetreatmentgrouptreatedwithJavanicaOilEmulsionInjectioncombinedwithbleomycin．Thepatientswerefollowedupfor3months．Wecomparedtwogroups'KPSscoreincr

6、easerate，remis-sionrateandtherateofadversereactions．Ｒesults:Thetreatmentgroup'sKPSscoreincreaserate(72．2%)andthepatients're-missionrate(75%)weresignificantlyhigherthanthoseofthecontrolgroup(50%，52．8%)．Andtheadversereactionrate(8．3%)wassignificantlylowerthanthatofthec

7、ontrolgroup(13．9%)．Therewassignificantdifference(P＜0．05)．Conclusion:JavanicaOilEmulsionInjectioncombinedwithbleomycintreatmentofprimarylungcancerwithmalignantpleuraleffusionhasbettercurativeeffectthanpurewesternmedicinetreatmentandhashighersecurity．Itisworthyofclinic

8、alpromotionandhastheclinicalimportanceoffunctionandmeaning．Keywords:JavanicaOilEmulsionInjection;bleomycin;combinedtraditionalChine