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时间:2019-05-24
《《不同手术治疗原发性肝癌疗效及其预后影响因素分析-论文》》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、检验医学与临床2O14年5月第11卷第9期IabMedClin,May2014,Vo1.11,No.9·1191··论著·不同手术治疗原发性肝癌疗效及其预后影响因素分析施文武,游红勇,李兵(四川省崇州市人民医院普外科611230)【摘要】目的探讨比较解剖式和非解剖式肝切除术治疗原发性肝癌(HCC)的手术疗效及其影响因素分析。方法将78例HCC患者按照手术方式的不同随机分为解剖式和非解剖式肝切除术组,每组各39例,对比两种手术方式的临床疗效,术中出血量、手术时间、住院时间、术后平均禁食时间、平均腹腔引流时间、并发症发生率及生存率指标,并筛选影响预后的因素。结果术后解剖
2、组和非解剖组的总体有效率和住院时间比较差异无统计学意义(P>0.05);但解剖组平均出血量、禁食时间、腹腔引流时间、并发症的发生率均明显低于非解剖组,而手术时间则明显高于非解剖组,差异均有统计学意义(P<0.05);解剖组生存率优于非解剖组,且与肿瘤大小、门静脉浸润、切缘和乙肝显著相关(P<0.05)。结论解剖式肝切除术虽操作复杂,但治疗HCC的临床疗效和安全性均优于非解剖式切除术,且能更好提高术后生存率。【关键词】原发性肝癌;肝切除;影响因素DOI:10.3969/j.issn.1672-9455.2014.09.017文献标志码:A文章编号:1672—9455(
3、2014)09一¨9I-02Effectscomparisonofdifferentliverresectionsurgeryinpatientswithhepat0ceUularcarcinomaandanalysisoffactorsinfluencingprognosisSHIWen—wa,YOUHong—yong,L1Bing(DepartmentofGeneralSurgery,PeoplesHospi—talofChongzhou,Chongzhou,Sichuan611230,China)[Abstract]ObjectiveTocomparethee
4、ffectsofanatomicalandnon-anatomicalliverresectionsurgeryinpatientswithhepatocellularcarcinoma(HCC)andtoanalyzethefactorsinfluencingprognosis.MethodsAtotaIof78patientswithHCCweredividedintoanatomiealandnon-anatomical1iverresectiongroup,with39casesineachgroup.Clinicalefficacy,bloodloss,o
5、perativetime,durationofhospitalization,postoperativemeanfastingtime,averageperitonealdrainagetime,incidenceofcomplicationsandindicatorsofsurvivalratewerecomparedbetweenthetwogroups,andfactorsinfluencingprognosiswerescreened.ResultsTherewerenosignificantdifferencesofclinicalef—ficiencya
6、nddurationofhospitalizationbetweenthetwogroups(P>0.05).Theaverageamountofbleeding,fastingtime,peritonealdrainagetimeandincidenceofcomplicationsinanatomicalgroupweresignificantlylowerthannon-anatomicalgroup,whiletheoperativetimewaslonger(P7、nnon—anatomicalgroup,whichwascorrelatedwithtumorsize,portalveininvasion,surgiealmarginandhepatitisB(P<0.05).ConclusionAlthoughanatomicliverresectionoperationmightbecomplex,butitsefficacyandsafetyinthetreatmentofHCCcouldbebetterthannon-anatomicalresection,andcouldimprovesurvivalrate.[
7、nnon—anatomicalgroup,whichwascorrelatedwithtumorsize,portalveininvasion,surgiealmarginandhepatitisB(P<0.05).ConclusionAlthoughanatomicliverresectionoperationmightbecomplex,butitsefficacyandsafetyinthetreatmentofHCCcouldbebetterthannon-anatomicalresection,andcouldimprovesurvivalrate.[
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