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1、ChineseJournalofNewDrugs2005,Vol.14No.11中国新药杂志2005年第14卷第11期物制剂的研究与开发。联系电话:(024)23911736,E2mail:propertiesandmechanismofdrugreleasefromethylcellulosematrixtangpharm@sina.com。tabletspreparedbydirectcompressionandhot2meltextrusion[J].IntJPharm,2004,269(2)∶509-52
2、2.[参考文献][7]MehuysE,VervaetC,RemonJP.Hot2meltextrudedethylcelluloseR○cylinderscontainingaHPMC2Gelucirecoreforsustaineddrug[1]NakamichiK,NakanoT,YasuuraH.Theroleofthekneadingpaddledelivery[J].JControlledRelease,2004,94(223)∶273-280.andtheeffectsofscrewrevolutio
3、nspeedandwatercontentonthe[8]RepkaMA,GuttaK,ProdduturiS,etal.Characterizationofcellulosicpreparationofsoliddispersionsusingatwin2screwextruder[J].IntJhot2meltextrudedfilmscontaininglidocaine[J].EurJPharmPharm,2002,241(2)∶203-211.Biopharm,2005,59(1)∶189-196.[2
4、]HülsmannS,BackensfeldT,KeitelS,etal.Meltextrusion2an[9]CrowleyMM,FredersdorfA,SchroederB,etal.Theinfluenceofalternativemethodforenhancingthedissolutionrateof17β2estradiolguaifenesinandketoprofenonthepropertiesofhot2meltextrudedhemihydrate[J].EurJPharmBiophar
5、m,2000,49(3)∶237-242.polyethyleneoxidefilms[J].EurJPharmSci,2004,22(5)∶409-[3]PerissuttiB,MichaelB,NewtonJM,etal.Preparationofextruded418.carbamazepineandPEG4000asapotentialrapidreleasedosageform[10]ForsterA,HempenstallJ,TuckerI,etal.Selectionofexcipientsfor[
6、J].EurJPharmBiopharm,2002,53(1)∶125-132.meltextrusionwithtwopoorlywater2solubledrugsbysolubility[4]VerreckG,SixK,MooterGV,etal.Characterizationofsolidparametercalculationandthermalanalysis[J].IntJPharm,2001,dispersionsofitraconazoleandhydroxypropylmethylcellu
7、loseprepared226(122)∶147-161.bymeltextrusion2parΙt[J].IntJPharm,2003,251(122)∶165-174.[11]BreitenbachJ.Meltextrusion:fromprocesstodrugdeliverytechnology[5]邓莉,邹豪,蒋雪涛.水飞蓟宾固体分散体的制备及体外溶出[J].EurJPharmBiopharm,2002,54(2)∶107-117.研究[J].第二军医大学学报,2000,21(10)∶961-964.[
8、6]CrowleyMM,SchroederB,FredersdorfA,etal.Physicochemical(接受日期:2005-05-08)3水蛭素滴眼液的研究崔莉,李运曼,孙宇,夏仁睿,欧瑜,吴梧桐(中国药科大学生命科学与技术学院,南京210009)[摘要]目的:制备水蛭素滴眼液,考察其稳定性及其对白内障防治作用。方法:以溶红细胞试验筛选促吸收3剂,用正交试验(L
