欢迎来到天天文库
浏览记录
ID:38113816
大小:397.97 KB
页数:4页
时间:2019-05-24
《鼻腔鼻窦内翻性乳头状瘤恶变因素的探讨》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·138·堕医药杂志2009年月第38卷第2期上半月ShanxiMedJ,February2009,Vo1.38,No.2theFirst等[17报道TLR4活化后通过影响郎格罕斯等抗原递呈细signalsfromtoll—likereceptors.Science,2004.304:1014—1018.胞参与银屑病的发病过程。11OjedaR,Santhez-ReganaM,MKssanaJ,eta1.Clinicalexperiencewiththeuseofeyelo6porinAinpsoriasis.Resul
2、tsofaretrospec—.综上所述,银屑病是一种难以治愈的慢性皮肤炎症性皮肤病,严重影响患者的生活质量。TLR在免疫识别和炎tivestudy.JDermatolTreat,2005,16(4):238.241.12BakerBS,OvigneJM,PowlesAV,eta1.Normalkeratinocyteex—症反应中的关键作用以及TLR与银屑病的密切关系引起pressTbll—likereceptors(TLRs)1,2and5:modulationofTLR学者的兴趣,TLR可能为银屑病的治疗提供新的靶
3、点。目expressioninchronicplaquepsoriasis.BrJDermatol,2003,148:前已有TLR激动剂等药物应用于制备疫苗和癌症、感染性670.679.疾病、哮喘等疾病的实验性治疗[18_。随着研究的不断深13BegonE,MichelL,FlageulB,etat.Expression,subcellularlocal—入,TLR可能会给我们带来更多的惊喜。izationandeytokiniemodulationof。ll—likereceptors(TLRs)in参考文献nOlTl
4、lalhumankeratinocytes:TLR2up—regulationinpsoriatic1AlegreML,GoldsteinDR,ChongAS.1’0ll—likereceptorsignalingskin.EurJDerrrmtol,2007,17(6):497.506.intransplantation.CurrOpinOrganTransplant,2008,13(4):14CurryJL,QinJZ,BonishB,etat.Innateimmune—relatedreceptors358.365
5、.innormalandpsoriaticskin.ArchPatholLabMed,2003,127:2WardleEN.,I’0ll—likereceptorsandglomerulonephritis.SaudiJ178.186.KidneyDisTransplant,2007,18(2):159—172.15GillietM,ConradC,GeigesM,etat.Psoriasistriggeredbytoll-3HoshinoK.KaishoT.NucleidacidsensingToll—likerece
6、ptorsinlikereceptor7agonistimiquimodinthepresenceofdermalplas—dendriticcells.CurrOpinImmunol,2008,20(4):408—413.macytoiddendriticeellprecursors.ArchDermatol,2004,140:4SteinD,RothS,VogelsangE,etat.Thepolarityofthedorsoven—1490。1495.trataxisintheDrosophilaembryoisd
7、efinedby811extraeellular16B&rl'atFJ。CoffmanRL.DevelopmentofTLRinhibitorsforthesigna1.Cell,1991,65:725—735.treatmentofautoimmunediseases.ImmunoIRev,2008,223:271—5GayNJ.GangloffM.StructureandfunctionofT。Ureceptorsand281.theirligands.AnnRevBiochern,2007,76:141-165.1
8、7RifI【inIR,LeadbetterEA,BusconiL,etat.Toll—likereceptors,el1一61wasakiA.MedzhitovR.T。ll—likereceptorcontroloftheadaptivedogenousligands,andsystemicautoimmunedis
此文档下载收益归作者所有