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时间:2019-05-22
《手术切除联合角膜缘干细胞移植、羊膜移植及单纯手术切除治疗翼状胬肉临床疗效分析》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、Vo1.23No.4February2012HAINANMEDICALJOURNAL《海南医学)2012年第23卷第4期doi:10.3969/j.issn.1003—6350.2012.04.019·临床研究·手术切除联合角膜缘干细胞移植、羊膜移植及单纯手术切除治疗翼状胬肉临床疗效分析潘智,黄光初(钦州市第一人民医院眼科二区,广西钦州535000)【摘要】目的探讨手术切除联合角膜缘干细胞移植、羊膜移植及单纯手术切除治疗翼状胬肉的临床疗效。方法选择本院2008年3月至2010年5月收治的角膜缘翼状胬
2、肉患者9O例,随机分为三组,角膜移植组给予手术切除联合角膜缘干细胞移植,羊膜移植组给予手术切除胬肉联合羊膜移植治疗,单纯手术组仅给予翼状胬肉手术切除;观察三组治疗效果。结果三组术后随访两年,角膜移植组、单纯手术组术后创面愈合时间短于羊膜移植组,差异有统计学意义(P<0.05),角膜移植组创面愈合时间与单纯手术组差异无统计学意义(P>O.05);角膜移植组术后治愈28例,复发2例,羊膜移植组术后治愈25例,复发5例,单纯手术组术后治愈22例,复发8例,三组术后复发率比较,差异有统计学意义(P<0.05
3、)。结论手术切除联合角膜缘干细胞移植治疗翼状胬肉,术后复发率低,并发症少,愈合时间短,值得应用。【关键词】翼状胬肉;角膜缘干细胞;羊膜;手术切除【中图分类号】R779.6【文献标识码】A【文章编号】1003—635O(2012)O4一O45—03Comparativeanalysisofsurgicalexcisioncombinedwithlimbalstemcelltransplantation,amnioticmembranetransplantationandsurgeryalonefort
4、hetreatmentofpterygiam.PANZhi,HUANGGuang—Chu.DepartmentofOphthalmology,theFirstPeople'sHospitalofQinzhou,Qinzhou535000,Guangxi,CHINA【Abstract】ObjectiveOevaluatetheclinicaleficacyofsurgicalexcisioncombinedwithlimbalstemcelltransplantation,amnioticmembra
5、netransplantationandsu~eryaloneforthetreatmentofpterygium.Methods90pterygiumpatientsfromMarch2006toMay2010wererandomlydividedintocornealtransplantationgroup,amnioticmembranetransplantationgroup,surgerygroup,with30caseseachgroup.Cornealtransplantationgr
6、oupweretreatedwithsurgicalexcisionpluslimbalstemcelltransplantation,amnioticmembranetransplantationgroupweretreatedwithsurgicalexcisionplusamnioticmembranetransplantation,andsurgerygroupwithsurgicalexcisiononly.Thetreatmentefectsofthreegroupswereobserv
7、ed.ResultsAllthepatientsinthreegroupshadbeenfollowedupfor2years;woundhealingtimeofcornealtransplantationgroupandsurgerygroupwasshorterthanthatofanmioticmem—branetransplantationgroup,、vimthestatisticallysignificantdiference(尸8、alingtimebetweencornealtransplantationgroupandsurgerygroupwasnotstatisticallysignificant;28casesofeome~transplanta—tiongroupwerecured,andrecurrencein2cases;25casesofamnioticmembranetransplantationgroupwerecured,andrecurrencein5cases;22c
8、alingtimebetweencornealtransplantationgroupandsurgerygroupwasnotstatisticallysignificant;28casesofeome~transplanta—tiongroupwerecured,andrecurrencein2cases;25casesofamnioticmembranetransplantationgroupwerecured,andrecurrencein5cases;22c
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