沙眼衣原体生殖道感染诊治指南

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1、2006UKNationalGuidelinefortheManagementofGenitalTractInfectionwithChlamydiatrachomatisIntroductionandMethodologyScopeandPurposeThemainobjectiveistoreducethenumberofsexuallytransmittedinfections(STIs)andthecomplicationsthatcanariseinpeopleeitherpresentingwithsignsandsymptomsofa

2、nSTI,orundergoinginvestigationforpossibleinfection.Specifically:Thisguidelineoffersrecommendationsonthediagnostictests,treatmentregimensandhealthpromotionprinciplesneededfortheeffectivemanagementofC.trachomatis.Itcoversmanagementoftheinitialpresentation,aswellashowtopreventtra

3、nsmissionandfutureinfection.Itisaimedprimarilyatpeopleaged16yearsorolder(seespecificguidelinesforthoseunder16)presentingtohealthcareprofessionals,workingindepartmentsofferinglevel3careinSTImanagement(seenationalstrategy)withintheUnitedKingdom.However,theprinciplesoftherecommen

4、dationsshouldbeadoptedacrossalllevels(levels1and2mayneedtodevelop,whereappropriate,localcarepathways).StakeholderInvolvementThisguidelinehasbeenproducedbymedicalspecialistsfromrelevantdisciplineswithinputfrompatientsattendingUKGUMclinics.SuccessivedraftshavebeenreviewedbyGUMpa

5、tients,GUMphysicians,nurses,healthadvisersandkeyprofessionalorganisations.RigourofDevelopmentAnextensiveliteraturereviewedwascarriedoutusingMedlinesearchesfortheyears1970to2001usingkeywords“Chlamydiatrachomatis”inassociation1with"polymerasechainreaction”or“PCR”or“ligasechainre

6、action”or“lcr”or“lcx”and“immunoenzymetechniques”or“enzyme-linkedimmunosorbentassay”.“Chlamydiatrachomatis”combinedwiththefollowingkeywords“detection”,“diagnosis”,“treatment”.TheCochranelibrary:“Chlamydiatrachomatis”.Thisliteraturesearchwasupdatedin2005andincludednucleicacidamp

7、lificationtechnique,Aptima,ProbetecandSDA.What’sNew?NAATstobeusedformedico-legalcasesEIAstobereplacedbyNAATsUpdateonperformancesofNAATsOfferepidemiologicaltreatmenttocontactsofC.trachomatisasperindexcase.Azithromycin1gmstatinpregnancyrecommendedbyWHO;unlicensedinUK(2006).BNFre

8、commenduseonlyifnootheralternativeavailable.Recommendationfor