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ID:36653297
大小:1.16 MB
页数:34页
时间:2019-05-13
《增损双解散防治温病气分证发热的实验研究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、山东中医药大学硕士学位论文增损双解散防治温病气分证发热的实验研究姓名:宋素花申请学位级别:硕士专业:中医临床基础指导教师:董锡玑2003.4.20提要目的:温热毒邪是温热性温病发病的重要因素,阳热火毒内郁,气机升降失常为其基本病机。增损双解散具有清热解毒,调畅气机的作用,正是治疗“温病表里大热”的重要方剂。本课题从动物实验方面对增损双解散防治温热病气分发热的作用机理及其优势进行了初步探讨,以期对临床有所裨益。方法:在中医传统理论的指导下,结合现代医学理论知识和手段,用肺炎双球菌制造家兔温病气分证发热模型,将增损双解散组作为实验组,并设立双解
2、散组作为对照组,观察实验前后动物的体温、血清超氧化物歧化酶(SOD),血清丙二醛(MDA)及白细胞计数检查的变,、化,以及组织器官的病变程度N结果:增损双解散具有良好的降温作用,能提高动物的SOD水平,降低MDA水平,明显减损双解散在多数观察指标上疗效优于双解织器官的病变程度。数据表明增:增损双解散是防治温热病气分发热的重要方剂,提示在治疗温热病阳热火毒内郁、气机升降失常,表里阻隔时,总以调畅气机为其要义。关Rir,q温热性温病;气分证;增损双解散;调畅气机;妄验研叉ExperimentaIStudyonTreatmentfor0ifenS
3、tageofSeasonaFebriIeDiseaseWithZengSunShuangJiePowderSpeciaIity:The0IinicaIandBasiCSubJectofT.C.MAuthor:SongSuhuaTutor:DongXijiAbstractObjectiVe"Warm-heatevilistheimportantpathogemcfactorofseasona/fabriledisease,andheat-evilstasis,ascent-descentdisorderofvisceralqiisbasicp
4、athogenesis.ThefunctionofZengSunShuangJie亿SSJ)powderisclearingawayheatandtoxicmaterials,activatingfunctionalactivitesofQi.ThisarticlestudytheeffectofZSSJpowderintreatingQifenstageofseasonalfabrilediseasebywayoftheanimalexperiment.Methods:24domesticrabbitsweredividedintofou
5、rgroupsrandomly.Thepneumoniab∞terialWasinjectedintoallrabbits,exceptingrabbitsinnormalgroup.ZSSJpowderWasgiventotreatmentclassmcluding6rabbits.AtthesametimeShuangJie(sJ)powderWasgiventocontrolclassincluding6rabbits.Observethechangeoftemperature,SOD,MDA,thenumberofwhitecell
6、,thepathogenicdegreeof]ungtissueinrabbits.ResuIts:TheresultsrevealthatZSSJpowderCanmcreasethelevelsofSOD,decreasethelevelsofMDA,andprotectanimal’Sphysicalorgan.StasisshowsthatZSSJpowd盯issuperiortoSJpowder.ConcIusion:ZSSJpowderisaeffectiveprescriptionintreatingQifenstageofs
7、easonalfebriledisease.WeshouldattachgreatsignificancetotreatingseasonalfebrilediseasebyactivatingfunctionalactivitiesofQi.Keywordsseasonalfebriledisease;Qifenstage;ZengSunShuangJiepowder;activatefunctionalactivitiesofQi;experimentalsmdy堂塑翌竺苎堕兰墨堕墨坌堡垒垫竺壅竺竺墨—————————————一引言温病
8、是以感受温邪为主因而引起的一类急性外感热病,其中温热性温病尤为多见,而其气分证,则是该病发展过程中病程较长、涉及脏腑最多、病理变化最为复杂多样的一个病理阶段。而阳热火毒内郁,表里
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