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1、上海交通大学硕士学位论文Pentacam的临床应用研究姓名：吕雪婷申请学位级别：硕士专业：眼科学指导教师：祝肇荣20080401－0.022角膜厚度。结论：眼前节各参数与年龄因素有显著相关性。随着年龄增大，中央角膜厚度的改变不大，而前房容积和前房角随之变小，前房深度随之变浅，这可能是老年性晶体增厚的结果。男女性别之间前房参数的差异大多出现在60岁之后，即60岁后，女性发生闭角型青光眼的可能性远大于男性。中央角膜厚度与矫正眼压（corIOP）显著相关。Pentacam能对眼前节各参数进行准确测量并早期筛查
2、原发性闭角型青光眼。关键词：青光眼，眼前房，三维Scheimpflug图像CLINICALRESEARCHOFPENTACAMABSTRACTObjective：Tomeasureandanalysecentralcornealthickness,chambervolume,angle,anteriorchamberdepthandcorrectedintraocularpressureofnormaleyesbyPentacamthree-dimensionanteriorsegmentanalyze
3、r.Trytosetupeffectiveearlydiagnosticparametersforscreeningprimaryangle-closureglaucoma[PACG]andtolaythegroudworkfortheclinicalapplicationofPentacam.Methods：221people(442eyes)wereenrolledinthestudy.Theyweredevidedinto5groupsbyage,50peoplewereunder40y,50we
4、rebetween40yand50y,50werebetween50yand60y,50werebetween60yand70y,21wereover70y.AllofthemunderwentPentacamexaminations.Mainparametersincludedcentralcornealthickness,chambervolume,angle,anteriorchamberdepthandcorrectedintraocularpressure.Results：Statistica
5、llysignificantdifference(P<0.05)werefoundbetweendifferentagegroupsinchambervolume,angleandanteriorchamberdepth.Chambervolumewasstableafter70y;anglebecamesmallerafter40yandbecameevensmallerafter60y,itwasaninterimbetween40yand60y,andalsohardlychangedafter7
6、0y;anteriorchamberdepthbecameshallowerafter40y.Inalltheagegroups,chambervolume,angleandanteriorchamberdepthin60y—70ygroup,andchambervolumeandanteriorchamberdepthinover70groupweresignificantlydifferentwithgender.Centralcornealthicknesswassignificantlycorr
7、elatedwithcorrectedintraocularpressure(corIOP)(P<0.01,theSpearmancorrelationcoefficientwas－0.287),corIOP=27.509－0.022centralcornealthickness.Conclusion：Anteriorsegmentparametersoftheagearesignificantlycorrelatedwithage.Centralcornealthicknessisstable,whi
8、lechambervolumeandanglebecomesmallerandanteriorchamberdepthbecomeshallowerprobablyduetoagerelatedlenschangesinoldpeople.After60y,theanterioreyesegmentparametersbecomesignificantlydifferentwithgender.Thatistosay,female.Thec
