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1、医学微生物学和免疫学教学大纲(TeachingoutlineofmedicalmicrobiologyandImmunology)TeachingoutlineofmedicalmicrobiologyandImmunology(forclinicalmedicine,nursing,oralandotherspecialistuse)DepartmentofMicrobiologyandimmunology,Schoolofmedicine,ShantouUniversityTwo,00,two,MayTeachi
2、ngoutlineofmedicalmicrobiologyandImmunologyThissyllabusisrevisedaccordingtothefourtheditionofmedicalmicrobiologyandimmunology,editedbyZhangZhuoran,anationalmedicalcollegetextbook,editedfromtheoriginalsyllabus.Forclinicalmedicine,nursing,dentalstudents(threeyear
3、)learningreference.Thecontentsofeachchapterintheoutlinearemastered,understoodandunderstoodinthreelevels.Inordertograspthecontent,thelineismarkedasamarkunderthetext;ifthecontentisrequiredtobefamiliar,thedottedlineismarkedasthemarkunderthetext;thereporterisnotfam
4、iliarwiththecontent.IntroductionTheconceptanddevelopmentofmedicalimmunologyandmedicalmicrobiology.Theconceptandspeciesofmicroorganismsandtherelationshipbetweenmicroorganismsandhumanbeings.Currentstatusofimmunologyandmicrobiologyinchina.ThefirstMedicalImmunology
5、FoundationOverview:theconceptofimmunityanditsthreefunctions(immunedefense,immunestabilityandimmunesurveillance).Theacquisitionofimmunefunction:nonspecificimmunityandspecificimmunity.Compositionandcharacteristicsoftheimmunesystem.Chapter1antigenTheconceptofantig
6、enanditstwoproperties(immunogenicityandimmunoreactivity).Classificationofantigens:theconceptofcompleteantigenandincompleteantigen(hapten).Thymusdependentantigen(TdAg)andnonthymusdependentantigen(TiAg).Endogenousantigen(autoantigen)andexogenousantigen(heterologo
7、usantigen,ISOantigen),allogeneicantigen.Allergenandtolerance.Theconditionsofimmunogenicity:foreignbody,macromolecularsubstance,chemicalcompositionandmolecularstructure.Specificityandcrossreactivityofantigens:conceptsofspecificity,antigenicdeterminants,antigenbi
8、ndingvalenceandcrossreactivity.Medicallyimportantantigen:pathogenicmicroorganisms,bacterialtoxinandtoxoid,animalserum(dualityofbody),heterophileantigen,allogenicantigen(redc