mir-129-1-3pmir-129-2-3p在浆液性卵巢癌中的表达及其相关功能的初步研究

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1、分类号R711.75第四军医大学UDC618TheFourthMilitaryMedicalUniversity密级公开硕士学位论文miR-129-1-3p/miR-129-2-3p在浆液性卵巢癌中的表达及其相关功能的初步研究刘菲培养类别全日制学位类型专业学位一级学科(专业类)临床医学二级学科(专业)妇产科学研究方向卵巢癌发生分子机制研究指导教师李艳红副教授（副主任医师）培养单位唐都医院妇产科二O一五年五月第四军医大学硕士学位论文目录缩略语表·············································································

2、································1中文摘要·············································································································3英文摘要·············································································································6前言·····································

3、·······································································10文献回顾············································································································12正文············································································································21第

4、一部分miR-129-1-3p/miR-129-2-3p在浆液性卵巢癌组织中的表达··············211材料···························································································212方法···························································································223结果················································

5、···········································254讨论···························································································27第二部分miR-129-1-3p/miR-129-2-3p在浆液性卵巢癌细胞Skov3中的相关功能研究·291材料···························································································292方法······

6、·····················································································303结果···························································································344讨论···························································································37第三部分miR-129-1-3p/miR-

7、129-2-3p靶基因的生物信息学分析及验证···········381材料···························································································382方法··································································