膝骨关节炎患者软骨容积与关节结构及脂肪细胞因子相关性临床研究

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1、分类号8______________密级：_________________UDCt编号：学位论文膝骨关节炎患者软骨容积与关节结构及脂肪细胞因子相关性临床研究Correlationsofcartilagevolume^structurechangesandadipokinesinpatientswithkneeosteoarthritis郑双指导教师姓名徐建华教授安徽医科大学第一附属医院申请学位级别硕士专业名称内科学（风湿病）提交论文日期201543-15论文答辩日期2015-05-14学位授予单位和日期安徽医科大学答辩委员会主席刘健教授

2、评阅人盲审2015年05月学位论文独创性声明本人所呈交的论文是我个人在导师指导下进行的研究工作及取得的研究成杲。据我所知，除了文中特别加以标注和致谢的地方外，论文中不包含其他人已经发表或撰写过的研究成果。与我一同工作的同志对本研究所做的任何贡献均已在论文中作了明确说明并表示谢意。学位论文作者签名：外u期：$_V/_学位论文使用授权声明本人完全了解安徽医科大学有关保留、使用学位论文的规定••学校有权保留学位论文并向国家主管部门或其指定机构送交论文的电子版和纸质版，有权允许论文进入学校图书馆被查阅，有权将学位论文的内容编入有关数据库进行检索，

3、有权将学位论文的标题和摘要汇编出版。愿意将本人的学位论文提交《中囯优秀硕士学位论文全文数据库》和《中国学位论文全文数据库》中全文发表，并可以以电子、网络及其他数字媒体形式公开出版，并同意编入CNKI《中国知识资源总库》，在《中囯博硕士学位论文评价数据库》中使用和在互联网上传播。保密的学位论文在解密后适用本规定。安徽医科大学ANHUIMEDICALUNIVERSITY硕士学位论文论文题目膝骨关节炎患者软骨容积与关节结构及脂肪细胞因子相关性临床研究Correlationsofcartilagevolume,structurechangesan

4、dadipokinesinpatientswithkneeosteoarthritis作者姓名郑双指导教师徐建华教授学科专业内科学（风湿病）研究方向代谢性炎症在骨关节炎发病机制中作用论文工作时间2013年2月至2015年3月目录一．中英文缩略词表········································1二．中文摘要·············································3三．英文摘要··········································6四．正文1.引

5、言··············································92.材料与方法（1）病例选择与入组··································12（2）标本采集·······································14（3）实验方法··········································14（4）影像学检测···········································16（5）分组标准············

6、·································22（6）统计学方法········································223.结果················································234.讨论················································425.结论····················································466.参考文献···············

7、·································46五．附录··············································54六．致谢················································90七．综述及综述参考文献···································91安徽医科大学硕士学位论文中英文缩略词表Abbreviation英文缩写英文全称中文全称AAnterior前侧ACRAmericanCollegeofRheumatol

8、ogy美国风湿病学会ADPAdiponectin脂联素BMIBodyMassIndex体质指数BMLsBoneMarrowLesions骨髓病变CCentral中侧CDCartilageDef