糖尿病视网膜病变患者的泪膜改变

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1、授予单位代码10089学号或申请号13478HebeiMedicalUniversity硕士学位论文科学学位糖尿病视网膜病变患者的泪膜改变作者姓名：高志海导师：唐广贤主任医师专业：眼科学二级学院：石家庄市第一医院2015年03月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师(或指导小组)的指导下,由本人独立完成《«本学位论文研究所获得的研究成果,其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文,第一署名为单位河北医科大学，试验材料、原始数据、申报的专利等知识产权均归河北医科大学所有�否则，承担相应法律责任。pB—

2、1研究生导體章鮮_导_®/y/V年r月7/日河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果，除了文中特别加以标注和致谢等内容外,文中木包含其他人已经发表或撰写的研究成果,指导教师对此进行了审定。本论文由本人独立撰写,文责自负。研究生签名：导师签章：JC月；）日目录中文摘要·············································································1英文摘要······························································

3、···············5英文缩写·············································································10研究论文糖尿病视网膜病变患者的泪膜改变前言·············································································11材料与方法····································································11结果························

4、·····················································13附表·············································································15讨论·············································································17结论·············································································24参考

5、文献·······································································25综述糖尿病视网膜病变患者泪膜改变的研究现状·······················28致谢···················································································38个人简历·············································································39中文摘要糖尿病视网

6、膜病变患者的泪膜改变摘要目的：通过检测和比较分期不同的糖尿病视网膜病(diabeticretinopathy,DR)患者及正常健康人群的泪膜的系列指标,观察探讨糖尿病视网膜病变患者是否存在泪液分泌、泪膜功能的变化及角膜上皮的损伤情况。观察其相关指标是如何变化的，以及各个指标与糖尿病病程，DR分期等有何相关性。从而引起眼科医师重视，对于糖尿病视网膜病变患者，是否需要定期进行常规的泪膜功能检查，从而更早的确诊疾病，减少误诊或漏诊，防止并发症的发生。方法：1研究对象选择2014年1月到12月在我院眼科门诊就诊的由内分泌专业科室确诊为2型糖尿病的患者共80例（160只眼），其中男43例，女37例，年龄

7、（62±8.702）岁。对照组为同期在我院门诊就诊的非糖尿病患者，共66例（132只眼），其中男31例，女35例，年龄（62.152±8.258）岁。所有受试者均接受病史询问、干眼症状询问及相关检查。2自觉症状有无几大主要症状：干涩感、异物感、眼疲劳、烧灼感、不适感、视力波动等。3检查方法检查安排在同一间光线暗、较安静的室内，由经过培训的有经验的眼科医师操作检查。3.1泪液分泌试验（Schirme