通心络联合外周血间充质干细胞移植治疗糖尿病足的实验研究

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1、授予单位代码10089学号或申请号20121090HebeiMedicalUniversity博士学位论文科学学位通心络联合外周血间充质干细胞移植治疗糖尿病足的实验研究研究生：郭勇英导师：吴以岭教授专业：中西医结合临床二级学院：以岭医药集团2015年4月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师（或指导小组）的指导下，由本人独立完成。本学位论文研究所获得的研究成果，其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文，第一署名为单位河北医科大学，试验材料、原始数据、申报

2、的专利等知识产权均归河北医科大学所有。否则，承担相应法律责任。x'T77"^u>/左年4月刁曰河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研宂工作及取得的研究成果，除了文中特别加以标注和致谢等内容外，文中不包含其他人己经发表或撰写的研宄成果，指导教师对此进行了审定。本论文由本人独立撰写，文责自负。研究生签名：‘导师签年々月对日目录中文摘要··············································································1英文摘要················

3、······························································8英文缩写·············································································18研究论文通心络联合外周血间充质干细胞移植治疗糖尿病足的实验研究引言·············································································20第一部分脉络学说指导糖尿病足理论探讨前言

4、·············································································22中医学对糖尿病足的认识··················································22脉络学说指导糖尿病足理论探讨·········································27参考文献·······································································32第二

5、部分通心络联合外周血间充质干细胞移植治疗糖尿病足大鼠的作用研究前言·············································································38材料与方法····································································38结果·············································································44附图········

6、·····································································47附表·············································································53讨论·············································································58小结···········································

7、··································59参考文献·······································································60第三部分通心络联合外周血间充质干细胞移植对糖尿病足大鼠炎症反应、氧化应激和晚期糖基化终末产物的影响前言·············································································63材料与方法······························

8、······································63结果············