温阳益气活血利水法治疗扩张型心肌病心力衰竭的临床研究

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1、授予单位代码10089学号或申请号HebeiMedicalUniversity硕士学位论文科学学位温阳益气活血利水法治疗扩张型心肌病心力衰竭的临床研究作者姓名：王雷导师：苗华为教授专业：中西医结合临床二级学院：河北省中医院2015年03月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师(或指导小组)的指导下，由本人独立完成。本学位论文研究所获得的研究成果,其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文，第一署名为单位河北医科大学，试验材料、原始数据、申报的专利等知

2、识产权均归河北医科大学所有。否则，承担相应法律责任。„I君研究生签名导师签章：二级学院领导盖章：ti犮j年广月日河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果，除了文中特别加以标注和致谢等内容外，文中不包含其他人已经发表或撰写的研究成果，指导教师对此进行了审定。本论文由本人独立撰写,文责自负。IJP'S年厂月目录中文摘要··············································································1英文摘要···········

3、···································································4英文缩写··············································································8研究论文温阳益气活血利水法治疗扩张型心肌病心力衰竭的临床研究前言··············································································9材料与方法········

4、·····························································10结果··············································································14附表··············································································15讨论··············································

5、································16结论··············································································18参考文献········································································18综述中西医结合治疗扩张型心肌病的研究近况····························21致谢·····························

6、·······················································29个人简历··············································································30中文摘要温阳益气活血利水法治疗扩张型心肌病心力衰竭的临床研究摘要扩张型心肌病（dilatedcardiomyopathyDCM）是心肌病的常见类型，是一种以左室扩张并伴有收缩功能减退为特征的心肌病。中医古籍中无“扩张型心肌病”之名，据临床主要表现归属于中医“胸痹”“心

7、悸”“喘证”“饮证”和“水肿”之范畴。DCM导致左室收缩功能降低、进行性心力衰竭、室性和室上性心律失常、传导系统异常、血栓栓塞和猝死，是心力衰竭的第三位原因。扩张型心肌病可发生于世界各地。由于认识提高，发现本病的发病率、患病率和死亡率均有逐渐增高的趋势，并发现在热带、亚热带地区高发，个别地区本病占心脏病的首位。目前有关本病发病率和患病率的资料甚少，因此真正的发病率和患病率尚不清楚。在DCM的病理基础上，随着进行性充血性心力衰竭的不断进展，心功能不断下降，全身各系统均会受到影响，而西医治疗尚无特殊的防治方法，治疗原则是治疗充血性心力衰竭和各种心律

8、失常以及预防肺、体循环栓塞，延长患者寿命。西药在治疗DCM的过程中会产生各种不良反应，如ACEI和ARB常常恶化肾功能，螺内酯会导致高钾血症。这样又限