清肠化浊汤联合美沙拉嗪治疗慢性溃疡性结肠炎的临床研究

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1、授予单位代码10089_学号或申请号2012273】HebeiMedicalUniversity硕士学位论文科学学位清肠化浊汤联合美沙拉嗪治疗慢性溃疡性结肠炎的临床研究研究生：魏少兴导师：高记华教授专业：中西医结合临床二级学院：中医院2015年3月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师（或指导小组）的指导下，由本人独立完成。本学位论文研究所获得的研究成果，其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文，第一署名为单位河北医科大学，试验材料、原始数据、申报的

2、专利等知识产权均归河北医科大学所有。否则，承担相应法律责任。研宄生签名；导师签章级学院领导盖章:河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研宄成果，除了文中特别加以标注和致谢等内容外，文中不包含其他人已经发表或撰写的研宄成果，指导教师对此进行了审定。本论文由本人独立撰写，文责自负。研宄生签名:年S月目录中文摘要·············································································1英文摘要····················

3、·························································4英文缩写·············································································7研究论文清肠化浊汤联合美沙拉嗪治疗慢性溃疡性结肠炎的临床研究前言·············································································8材料与方法·····················

4、···············································9结果·············································································16附图··············································································17附表·······························································

5、···············20讨论·············································································23结论·············································································30参考文献·······································································31综述慢性溃疡性结肠炎的治疗进展·····

6、····································32致谢···················································································47个人简历·············································································48中文摘要清肠化浊汤联合美沙拉嗪治疗慢性溃疡性结肠炎的临床研究摘要目的：溃疡性结肠炎（ulcerativecolitis,UC）属炎症性肠

7、病，是一种慢性非特异性结肠炎症性疾病。由于其病因和发病机制尚不明确,诊断困难,病变范围广、病程长、治愈难度大,且愈后又常易复发的特点,目前临床上还缺乏相关特效治疗。近些年来其发病率呈明显增高趋势。因此深入探讨其病因病机及中医药疗法,对于提高治愈率，缩短病程，减少并发症，降低复发率,具有十分重要的意义。本课题以慢性持续型轻、中度溃疡性结肠炎属大肠湿热型患者为研究对象，循从祖国传统中医学的相关理论，依据湿邪、热邪对溃疡性结肠炎的致病特点，结合“浊毒理论”对本病的深刻认识，兼以相关脏腑的论治，施以清热解毒、化瘀止痛、生肌敛疮的治法，观察与评价自拟清肠化

8、浊汤灌肠治疗溃疡性结肠炎的临床疗效，以阐明湿热内蕴影响大肠传导运化导致溃疡性结肠炎的病因、病机、传变和治疗，以达到治病求因，整体辩证，对