红花黄色素和血栓通注射液治疗急性脑梗死疗效对比观察

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1、授予单位代码10089学号或申请号13033HitanHebeiMedicalUniversity硕士学位论文在职科学学位红花黄色素和血栓通注射液治疗急性脑梗死疗效对比观察学位申请人：杨锐导师：王晓鹏教授专业：神经病学二级学院：第二医院2015年3月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师(或指导小组)的指导下,由本人独立完成。本学位论文研究所获得的研究成果,其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文，第一署名为单位河北医科大学，试验材料、原始数

2、据、申报的专利等知识产权均归河北医科大学所有。否则,承担相应法律责任。，t'Hx研究生签名导师签二级学院领_盖章/Skir年$月乂曰yvff..-一w河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果,除了文中特别加以标注和致谢等内容外,文中不包含其他人已经发表或撰写的研究成果，指导教师对此进行了审定。本论文由本人独立撰写,文责自负。研究生签名:导师签章：^'1年目录中文摘要·································································

3、·············1英文摘要···············································································4研究论文红花黄色素和血栓通注射液治疗急性脑梗死疗效对比观察前言···············································································7资料与方法··························································

4、············9结果··································································12附图···············································································14附表···············································································17讨论·····················

5、························································20结论··············································································25参考文献····································································37综述脑梗死的临床治疗进展…………………………………………30致谢··························

6、·························································47个人简历·············································································48中文摘要红花黄色素和血栓通注射液治疗急性脑梗死疗效对比观察摘要目的：通过观察血栓通注射液和注射用红花黄色素对急性脑梗死患者的疗效及其对NIHSS评分、BI、血脂水平、颈动脉斑块大小及同型半胱氨酸的影响，评估其疗效及临床应用价值。方法：将180例脑梗死患者随机分

7、为红花黄色素组、血栓通组和对照组，各组均为60例。3组患者均给予戒烟限酒，饮食控制，适量运动等生活方式改变。治疗情况如下，对照组：奥扎格雷钠80mg加入0.9％生理盐水250ml中，静滴1次/日；乙酰谷酰胺0.5g加入0.9％生理盐水250ml中，静滴1次/日；依达拉奉30mg加入0.9％生理盐水100ml中，静滴2次/日；低分子肝素钙5000u皮下注射，2次/日，连续14天，并酌情使用甘露醇。红花黄色素组在对照组治疗的基础上加用红花黄色素100mg+生理盐水250ml，静滴1次/日，连续l4天。血栓通组在对照组治疗的基础上加用血栓通10

8、0mg+生理盐水250ml，静滴1次/日，连续l4天。各组对高血压、糖尿病、心脏病患者予以相关口服药物治疗。观察指标为①治疗前、治疗第7天及治疗后第14天脑梗死患者神经功能缺损程度评分（NIH