欢迎来到天天文库
浏览记录
ID:34753777
大小:997.29 KB
页数:31页
时间:2019-03-10
《颈内动脉闭塞患者临床表现与侧枝循环的关系及其影响因素》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、摘要目的探讨颈内动脉闭塞(interna]carotidarteryocclusion,ICAO)患者临床表现和侧枝循环之间的关系及其影响因素。方法回顾性分析63例ICAO患者,按临床表现分为:无症状组14例和症状组49例,其中症状组又分为短暂性脑缺血发作(TIA)组4例和脑梗死组45例;用CT血管成像(CTA)和经颅多普勒超声(TCD)评价其侧枝循环的建立情况;分析其危险因素和临床常用血液生化指标,探讨临床表现和侧枝循环之间的关系及其影响因素。结果1、三组中侧枝循环开放频率最多的均为前交通动脉(AComA)和后交通动脉(PComA
2、)的一级侧枝循环开放;眼动脉(OA)作为二级侧枝循环次之。症状组(TIA和脑梗死组)和无症状组之间侧枝循环(AcomA,Pcomf和Oi)的开放未发现有显著性差异。2、AComA或PComA或0A是否开放与是否发生脑梗死之间均无显著性差异。3、代偿不良组(侧枝循环数目<2)高血脂比率和超敏C一反应蛋白(hs—CRP)水平明显高于代偿良好组(侧枝循环数目≥2),两组间均有显著性差异(P3、明显低于无症状组(P4、itsrelatedfactorsinpatientswithinternalcarotidarteryocclusion(ICAO)Methods63patientswithICAOwereanalyzedretrospectively.Accordingtotheclinicalmanifestations,theyweredividedintotwogroups:asymptomaticgroup(n=14)andsymptomaticgroups,whichconsistoftransientischemicattack(T5、IA)group(n=4)andcerebralinfarctiongroup(n245).CTangiography(CTA)andtranscranialDoppler(TCD)wereusedtoevaluatecollateralcirculation,theriskfactorsandbloodbiochemicalindicatorswereanalyzedandtherelationshipbetweenclinicalmanifestationsandcollateralcirculationanditsrelate6、dfactorswerediscussed.Results1.Theprimarycollateralpathways(AComAandPcomA)openingwerethemostfrequencyofthethreegroups,thesecondarycollateralpathways(OA)wasthesecondNostatisticallysignificancewithcollateralcirculation(AcomA,PcomAandOA)wasfoundbetweensymptomaticgroups(TI7、Aandcerebralinfarctiongroups)andasymptomaticgroup.2.Therewasnostatisticallysignificancebetweencollateralpathways(AComAorPComAorOA)openingandcerebralinfarctions3.Thehyperlipidemiapercentageandhigh—sensitivityC—reactiveprotein(hs—CRP)levelofthepoorercompensationgroupwhic8、hnumberofcollateralcirculationwerelessthantwowashigherthanthatofthebettercompensationgroupwhichnumberweregreaterthano
3、明显低于无症状组(P4、itsrelatedfactorsinpatientswithinternalcarotidarteryocclusion(ICAO)Methods63patientswithICAOwereanalyzedretrospectively.Accordingtotheclinicalmanifestations,theyweredividedintotwogroups:asymptomaticgroup(n=14)andsymptomaticgroups,whichconsistoftransientischemicattack(T5、IA)group(n=4)andcerebralinfarctiongroup(n245).CTangiography(CTA)andtranscranialDoppler(TCD)wereusedtoevaluatecollateralcirculation,theriskfactorsandbloodbiochemicalindicatorswereanalyzedandtherelationshipbetweenclinicalmanifestationsandcollateralcirculationanditsrelate6、dfactorswerediscussed.Results1.Theprimarycollateralpathways(AComAandPcomA)openingwerethemostfrequencyofthethreegroups,thesecondarycollateralpathways(OA)wasthesecondNostatisticallysignificancewithcollateralcirculation(AcomA,PcomAandOA)wasfoundbetweensymptomaticgroups(TI7、Aandcerebralinfarctiongroups)andasymptomaticgroup.2.Therewasnostatisticallysignificancebetweencollateralpathways(AComAorPComAorOA)openingandcerebralinfarctions3.Thehyperlipidemiapercentageandhigh—sensitivityC—reactiveprotein(hs—CRP)levelofthepoorercompensationgroupwhic8、hnumberofcollateralcirculationwerelessthantwowashigherthanthatofthebettercompensationgroupwhichnumberweregreaterthano
4、itsrelatedfactorsinpatientswithinternalcarotidarteryocclusion(ICAO)Methods63patientswithICAOwereanalyzedretrospectively.Accordingtotheclinicalmanifestations,theyweredividedintotwogroups:asymptomaticgroup(n=14)andsymptomaticgroups,whichconsistoftransientischemicattack(T
5、IA)group(n=4)andcerebralinfarctiongroup(n245).CTangiography(CTA)andtranscranialDoppler(TCD)wereusedtoevaluatecollateralcirculation,theriskfactorsandbloodbiochemicalindicatorswereanalyzedandtherelationshipbetweenclinicalmanifestationsandcollateralcirculationanditsrelate
6、dfactorswerediscussed.Results1.Theprimarycollateralpathways(AComAandPcomA)openingwerethemostfrequencyofthethreegroups,thesecondarycollateralpathways(OA)wasthesecondNostatisticallysignificancewithcollateralcirculation(AcomA,PcomAandOA)wasfoundbetweensymptomaticgroups(TI
7、Aandcerebralinfarctiongroups)andasymptomaticgroup.2.Therewasnostatisticallysignificancebetweencollateralpathways(AComAorPComAorOA)openingandcerebralinfarctions3.Thehyperlipidemiapercentageandhigh—sensitivityC—reactiveprotein(hs—CRP)levelofthepoorercompensationgroupwhic
8、hnumberofcollateralcirculationwerelessthantwowashigherthanthatofthebettercompensationgroupwhichnumberweregreaterthano
此文档下载收益归作者所有