甲泼尼龙联合肾上腺素治疗ⅲ度喉梗阻的临床观察

《甲泼尼龙联合肾上腺素治疗ⅲ度喉梗阻的临床观察》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。

1、甲泼尼龙联合肾上腺素治疗III度喉梗阻的临床观察罗显荣吴蓉(仪陇县人民医院四川仪陇637600)【摘要】目的观察甲泼尼龙联合雾化肾上腺素治疗111度喉梗阻的疗效。方法治疗组20例急性喉炎合并III度喉梗阻患儿，应用小剂量甲泼尼龙静脉注射联合氧气驱动雾化吸入肾上腺素治疗。对照组应用地塞米松静脉注射，同时雾化吸入地塞米松治疗。结果入院经治疗lh后，治疗组20例患儿缺氧症状均得到改善，有效率100%,对照组4例病情好转，有效率仅为20.0%o治疗2h后，治疗组有效率100%,对照组有效率60.0%o两组疗效比较差异有统计学意义(P<0.05)o结论小剂量甲泼尼龙联合雾化吸入肾上腺素治疗II

2、I度喉梗阻起效快，疗效明显优于地塞米松静脉注射并同时吸入地塞米松，且不良反应小，可避免气管切开，值得临床推广使用。【关键词】甲泼尼龙肾上腺素喉梗阻【中图分类号】R45【文献标识码】A【文章编号】2095-1752(2012)13-0387-02ClinicalobservationofMethylprednisolonecombinedwithEpinephrineintreatingdegreeIlllaryngealobstructionLUOXian・rong,WURong(ThePeople’sHospitalofYilong,Yilong637600,Sichu

3、an)[Abstract]ObjectiveToobservetheefficacyinthetreatmentofdegreeIlllaryngealobstructionwithmethylprednisolonecombinedwithnebulizedepinephrine.MethodsTwentychildrenofacutelaryngitiswithdegree111laryngealobstructionintreatmentgroupusedasmalldoseofintravenousmethylprednisolonecombinedwithinhalatio

4、nofoxygen・drivennebulizedepinephrine.Twentychildreninthecontrolgroupusedintravenousandsynchronouslynebulizeddexamethasone.Bothgroupsreceivedantibioticsasadjunctivetherapyatthesametime.ResultsAfteronehour’streatment,inthetreatmentgroup,allchildren’shypoxiasymptomsimprovedwitha100%eff

5、ectiverate.Whileinthecontrolgroup,onlyfourchildren’shypoxiasymptomsimprovedwitha20.0%effectiverate.Aftertwohoursoftreatment,theeffectiverateincontrolgroupwasraisedto60.0%•Thediffereneebetweentheefficacyofthetwogroupswasstatisticallysignificant(P<0.05).ConclusionsThetreatmentofdegreeIIIlar

6、yngealobstructionwithasmalldoseofmethyprednisolonecombinedwithinhalationofnebulizedepinephrineiseffectiveandcanavoidatracheotomy.Theefficacyofthetreatmentisobviouslyhigherthanintravenousandsynchronouslynebulizeddexamethasoneanddeservescomplications.【Keywords]MethylprednisoloneEpinephrineLarynge

7、alobstruction小儿急性感染性喉炎常见于婴幼儿，起病急，进展快，易并发喉梗阻。IV度喉梗阻及III度喉梗阻经治疗无效者应立即行气管切开术抢救，如不及时治疗可危及生命⑴。但小儿气管切开存在一定的危险性及并发症，技术要求高，家长配合性差，一般县级医院难以及吋进行，容易延误抢救。我科应用小剂量甲泼尼龙联合氧气驱动雾化吸入肾上腺素治疗III度喉梗阻患儿，疗效满意，无i例行气管切开，报道如下。1资料和方法1.1一般资料我院儿科PICU2009年1月至201