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1、ReviewsandOverviewsAMeta-AnalysisofCognitiveRemediationinSchizophreniaSusanR.McGurk,Ph.D.Objective:Thisstudyevaluatedtheef-chosocialfunctioning(0.36),andasmallfectsofcognitiveremediationforimprovingeffectsizeforsymptoms(0.28).Theef-ElizabethW.Twamley,Ph.D.cognitiveperf
2、ormance,symptoms,andfectsofcognitiveremediationonpsycho-psychosocialfunctioninginschizophrenia.socialfunctioningweresignificantlystron-DavidI.Sitzer,Ph.D.Method:Ameta-analysiswasconductedgerinstudiesthatprovidedadjunctiveof26randomized,controlledtrialsofcog-psychiatric
3、rehabilitationthaninthoseGregoryJ.McHugo,Ph.D.nitiveremediationinschizophreniain-thatprovidedcognitiveremediationcluding1,151patients.alone.KimT.Mueser,Ph.D.Results:Cognitiveremediationwasasso-Conclusions:Cognitiveremediationpro-ciatedwithsignificantimprovementsducesmo
4、derateimprovementsincogni-acrossallthreeoutcomes,withamediumtiveperformanceand,whencombinedeffectsizeforcognitiveperformancewithpsychiatricrehabilitation,alsoim-(0.41),aslightlylowereffectsizeforpsy-provesfunctionaloutcomes.(AmJPsychiatry2007;164:1791–1802)Cognitiveimp
5、airmentisacorefeatureofschizophre-itspresumedeffectsonpsychosocialfunctioningandim-nia,withconvergingevidenceshowingthatitisstronglyprovedresponsetorehabilitation.Therefore,acriticalex-relatedtofunctioninginareassuchaswork,socialrela-aminationoftheeffectsofcognitiverem
6、ediationonfunc-tionships,andindependentliving(1,2).Furthermore,tionaloutcomesisnecessaryinordertodetermineitscognitivefunctioningisarobustpredictorofresponsetopotentialroleinthetreatmentofschizophrenia.psychiatricrehabilitation(i.e.,systematiceffortstoim-Inrecentyears,
7、thenumberofstudiesthatexaminedprovethepsychosocialfunctioningofpersonswithseverepsychosocialfunctioninghasgrownsufficientlytopermitmentalillness)(3),includingoutcomessuchaswork,so-acloserlookattheimpactofcognitiveremediation.Wecialskills,andself-care(1,4,5).Becauseofth
8、eimportanceconductedameta-analysisofcontrolledstudiestoevalu-ofcognitiveimpairmentinschizophrenia,ithasbeenatetheeffe
