围生期窒息后不同胎龄新生儿血清酶变化与颅脑ct表现的临床分析

《围生期窒息后不同胎龄新生儿血清酶变化与颅脑ct表现的临床分析》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。

1、山东大学硕士学位论文产儿主要以脑室周围白质损伤为特点。关键词：围生期窒息；新生儿；血清酶；计算机断层扫描；胎龄山东大学硕士学位论文ACLINICALSTUDYONCHANGESoFSERUMENZYMESANDCRANIOCEREBRALCTINNEONATESWITHPERINATALASPHYⅪADURINGDIFFERENTGESTATIONALAGESupervisor：Prof．AnLiABSTRACTObjectivesToinvestigatetheeffectsonneonatescausedo

2、fperinatalasphyxiaduringdifferentgestationalage．Methods48neonateswithperinatalasphyxia(experimentalgroup)and30normalcases(controlgroup)wereinvolved．Theserumenzymes，includeAspertateaminotransferase(AST)，lactatedehydrogenase(LDH)，a-hydroxybutyricaciddehydrogen

3、ase(a-HBDH)，weredetectedwithin24hafterbirthinbomgroups．AcontrastanalysisofresultsWasperformedbetweenthetwogroups．Skull-CTWasdoneinexperimentalgroupononedayfrompostnatal4to7days．Non—perinatalasphyxiafactorswhichduetochangesinactivitiesofserumenzymeswereexclud

4、edinbothgroups．Skull-CTexaminationbythe64rowspiralCTscannerperformedinexperimentalgroupononedayfrompostnatal4to7days．ThemethodWastoSCancontinuouslyupwardsfromthebaselinein56、，10millofeachlayer．Results：Theactivitiesofserumenzymesincreasedinexperimentalgroupco

5、mparedwiththatincontrolgroup．Thedifferencesinthetwogroupsweresignificantforterminfants(尸<0．05)andnotsignificantforpreterminfants(尸>0．05)．TheresultofSkull—CTexaminationshowed，Hypoxic—ischemicencephalopathyexistedinamajorityofexperimentalgroupexceptfor3terminf

6、antswhichwere3山东大学硕士学位论文almostnormal．TherewasLowdensityshadowofdifferentdegreesexistedincerebralparenchyma．Apartofcaseswerecombinedwithcerebralhemorrhage，mostofwhichWassubarachnoidhemorrhage．ThelowdensityshadowWasmainlylocatedincerebralcortexandsubcorticalwh

7、itematterforterminfantswhileinperiventricularwhitematterforpreterminfants．Lowdensityshadowlocatedincorticalandsubcorticalwhitematter(CTvalue<18Hu)inall21casesofterminfantsinexperimentalgroup，mainlyinthebilateralfrontal，temporal，parietalandoccipitallobe．Periv

8、entricularwhitematterwasinvolvedin6cases．Therewasventriculomegalyinonecaseandassubarachnoidhemorrhagein5casesascomplications．LowdensityshadowlocatedinPeriventricularwhitematter(CTvalue<14Hu)inal