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《中医辩证分型治疗寻常型银屑病临床疗效观察及对患者血清il-4、il-8、tnf-α水平影响的研究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、TCMsyndromedifferentiationpointstypetreatmentwithpsoriasisvulgarisclinicalcurativeeffectobservationandpatientserumIL-4,IL-8,TNF-αlevelinfluenceofresearchSpecialty:Dermatology,SurgeryofTCMTutor:ProfessorZhangXiaojieAuthor:FengXinxingAbstractObjective:ObservationonTCMsyndromedifferentiationtreatment
2、ofpsoriasisvulgarisanditseffectonserumIL-4,IL-8,TNF-αlevelsinfluence,preliminarydiscussqingrexiaoyintang,huayuxiaoyintang,congyinyinyangtanginthetreatmentofpsoriasismechanism.Methods:160caseswererandomlydividedintotwogroups,includingthetreatmentgroupforChinesemedicinediagnosisandclassificationtrea
3、tmentgroup,thedialecticaldividedintoxuerefengshengtype(typeⅠ),xueyurejietype(typeⅡ),xuexufengzaotype(typeⅢ),respectively,toqingrexiaoyintang,huayuxiaoyintang,congyinyinyangtangdrink,thecontrolgroupin40cases,toshuangtuyindrink.Everytwoweeksachai,fourweekspertreatment,wereobservedtwotreatment.Compar
4、edwithtwogroupsofclinicalcurativeeffect,testingthetreatmentgroupserumIL-4beforeandaftertreatment,IL-8,TNF-αlevelchanged.Results:theclinicaleffect:treatmentgroup,controlgroupwerecuredrateisrespectively77.68%,57.78%,twogroupshadsignificantdifference(p<0.05);thetreatmentgroup,controlgrouptotaleffecti
5、veratewere92.86%,82.22%,twogroupshadsignificantdifference(p<0.05).3monthsaftertreatment,twopatientswerecured,treatmentgroup,controlgrouprecurrencerateswere14.94%,28.57%,twogroupshadsignificantdifference(P<0.05).Cytokinedetectionresults:beforetreatment,theserumTNF-α,typeIinpatientswithelevatedIL-8l
6、evels,incomparisonwithhealthycontrolgroup,therewassignificantdifference(P<0.01);typeIIinpatientswithelevatedserumIL-4level,incomparisonwithhealthycontrolgroup,therewassignificantdifference(P<0.01);typeIIIpatientswithelevatedserumIL-8levels,andhealthincomparisontothecontrolgroup,therewassignificant
7、difference(P<0.01).Aftertreatment,patientswithtypeⅠserumTNF-α,IL-8leveldecreased,ascomparedwithbeforetreatment,therewassignificantdifference(P<0.01);typeIIinpatientswithserumIL-4leveldecreased,ascomparedwithbefor