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37.An S-type bypass can improve the hemodynamics in the bypassed arteries and suppress intimal hyperplasia along the host artery floor.pdf

37.An S-type bypass can improve the hemodynamics in the bypassed arteries and suppress intimal hyperplasia along the host artery floor.pdf

ID：34072167

大小：1.19 MB

页数：8页

时间：2019-03-03

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1、ARTICLEINPRESSJournalofBiomechanics41(2008)2498–2505www.elsevier.com/locate/jbiomechwww.JBiomech.comAnS-typebypasscanimprovethehemodynamicsinthebypassedarteriesandsuppressintimalhyperplasiaalongthehostarteryfloorabca,daYuboFan,ZaipinXu,WentaoJiang,XiaoyanDeng,KeW

2、ang,AnqiangSunaDepartmentofBioengineering,BeihangUniversity,37XueyuanRoad,HaidianDistrict,Beijing100083,ChinabDepartmentofVeterinaryMedicine,GuizhouUniversity,Guiyang,ChinacSichuanUniversity,Chengdu,ChinadTheFirstAffiliationHospital,DalianMedicalUniversity,Dalian,

3、ChinaAccepted11May2008AbstractThedevelopmentofdistalend-to-sideanastomoticintimalhyperplasia(IH)hasbeenattributedtotheflowdisturbanceandabnormalwallshearstress(WSS)distributionthere.ThegeometryofthebypasshasastronginfluenceontheflowpatternandWSSdistribution.Usingaca

4、ninemodelofend-to-sideanastomosis,a451S-typebypasswascomparedwith601,451and301conventionalbypassesinthetermofIHalongthehostarteryfloor.Numericalbloodflowsimulationswerealsocarriedouttocharacterizetheflowpatternsatthedistalpartsofthebypassedarteriesforthe4models.Ther

5、esultsshowedthattheaveragedintimathicknessesofthehostarteryfloorsforthe4bypassmodelswere119.50710.30mm(601),65.5676.53mm(451),45.2675.99mm(301)and47.6474.85mm(S-type),respectively,vs.9.8171.88mminthecontrolgroup(withoutbypasssurgery).Comparedwiththecontrolgroup,ne

6、ointimathicknessinall4bypassmodelswassignificantlyincreased,buttheneointimathicknessofthe451S-typebypasswasapparentlymuchbetterthanits451conventionalcounterpart,andwasasgoodasthe301conventionalbypass.ThenumericalsimulationrevealedanapparentswirlingflowpatternintheS

7、-typebypass,whichwasverydifferentthantheflowpatternsinthe3conventionalbypassmodels.ThisswirlingflowalteredtheoverallflowpatterninthedistalpartofthebypassedarteryandeliminatedthelowWSSzonealongthehostarteryfloor.TheimprovementinthetermofIHfortheS-typebypassismostlikel

8、yduetothealterationoftheoverallflowpatternandWSSdistributionbythegeometricalconfigurationoftheS-typebypass.r2008ElsevierLtd.Allrightsreserved.Keywords:S-typebypa

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