制何首乌化学成分及其质量标准研究

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1、制何首乌化学成分及其质量标准研究ABSTRACTIncomparison埘t11theherbsandnaturalmedicinesofothercountries，alloutstandingcharacteristicofChinesemateriamedicawasthatChinesemateriamedicamustbeprocessedbeforeusedforclinic．Theancientssaid，“Processingisasmuchastraining，leadingtheuntrainedsoldierscannotovercometheener

2、my,usingtheunprocesseddrugsishardtocurethediseases”，therefore，theprocessingisveryimportanttoChinesemateriamediea．ButthebasicreasonthattheprocessinghasgreataffecttothedrugpropertyandefficacyWasthechangeofthoseintemalsubstancesafterprocessed．Studythechemicalconstituents’changesofbeforeandaft

3、erprocessinghaveimportantsignificancetoclarifytheprocessingprincipleofChinesemateriamedicaandtoformulatethequalitystandard．Heshouwu，thedriedrootofPolygonummultiflorumThunb．Thecrudehavetheefficacyofdetoxication,eliminatingcarbuncleandlooseningboweltorelieveconstipation，andusedtotreatscroful

4、a,sores，carbuncle，rubella,pruritus，constipationandhyperlipidemia．RadixPoIygoniMultifloriPreparata，theprocessedproductsofRadixPolygoniMultiflori，havetheefficacyofreinforcingliverandkidney，tollifyingbloodandessence，blackenbeardandhair，strengthenthetendonsandbones，andusedtocurehemopenia，etiol

5、ate，vertigo，tinnitus，beardandhairgrayingearly，waistandkneeslassitude，limbnumbness，metrorrhagiaandleucorrhea,chronicmalariaandbodydeficiency，hyperlipidemia．ThisstudywanttoclarifythechangeofPolygonummultiflorumThunb．beforeandafterprocessedandformulatethescientificreasonablequalifyevaluationm

6、ethodofRadixPolygoniMultifloriPreparatabyextractingandseparatingthechemicalconstituentsofRadixPolygoniMultifloriPreparata．Onthisbasis，thethin—layerchromatography(TLC)identificationmethodfordistinguishingtheRadixPolygoniMultifloriandRadixPolygoniMultifloriPreparatawasestablished，theHPLCfing

7、erprintspectrumanalysismethodofRadixPolygoniMultifloriPreparatahavebeenstudied，andthemaineffectiveconstituentscontentsinPolygonummultiflorumThunb．whichaffectedbydifferentprocessedtechnologyandmethodhavebeenstudied．1LiteraturereviewTheresearchliteraturesofPolyg