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1、提要目的：通过理论探讨以及临床调查，研究吸烟与颈动脉粥样硬化患者的中医证候特征，并分析烟草烟雾病邪特征和致病机理，为卒中的一二级预防提供有益的中医防治思路。方法：选择颈动脉粥样硬化患者107例，其中吸烟组54例，非吸烟组53例，分别比较两组在一般资料，颈动脉IMT、斑块面积、厚度、动脉硬化积分、中医证候等方面的差异。结果：通过对吸烟组和非吸烟组统计结果的对比分析，发现吸烟组患病年龄较非吸烟组明显提前（P<0.05）。吸烟同时伴有高血压、血脂异常的患者数要高于非吸烟组，有统计学差异（P<0.05）。吸烟组的颈动脉IMT、中医火热症状积分、动脉硬化积分高于非吸烟组
2、，有统计学差异（P<0.05）。结论：吸烟能加快颈动脉粥样硬化的进程，使其患病年龄提前，病情加重。同时，吸烟不仅可以直接影响颈动脉粥样硬化的发生发展，还对其危险因素有显著影响，危险因素互相作用，加速颈动脉粥样硬化进展。烟草烟雾为集火、热、燥、涩、浊、毒为一身的复合型致病因素，长期吸食烟草烟雾可使吸烟者的体质逐渐改变，吸烟者的中医证候特征也逐渐趋于改变。关键词烟草烟雾；颈动脉粥样硬化；火热SmokingandcarotidatherosclerosisinclinicalresearchanditspathogenesisdiscussionSpeciality
3、:theclinicalstudyofneuro-medicaldiseaseofTCMAuthor:ChenZheTutor:Prof.DingYuanqingAbstractObjective:Throughtheoreticalresearchandclinicalinvestigation,studyofsmokingandcarotidatherosclerosisinpatientswiththesyndromeoftraditionalChinesemedicineandanalysisoftobaccosmoke,pathogencharact
4、eristicsandpathogenicmechanism,oneortwolevelsofpreventionforstrokeTCMPreventionandtreatmentthoughtofuseful.Methods:Selectionofpatientswithcarotidatherosclerosisin107cases,including54casesofnonsmokingsmokinggroup,groupof53cases,werecomparedbetweenthetwogroupsingeneral,carotidarteryIM
5、T,plaquearea,thickness,arteriosclerosis,TCMsyndromeintegraldifferences.Results:Thesmokinggroupandnonsmokinggroupstatisticalresults,foundthesmokinggroupofageofonsetisnon-smokinggroupsignificantly(P<0.05)inadvance.Smokingisaccompaniedbyhypertension,dyslipidemiapatientsnumberishigherth
6、anthatofthesmokinggroup,therewasstatisticallysignificantdifference(P<0.05).CarotidIMTofsmokinggroup,traditionalChinesemedicinehotsymptomsintegral,arteriosclerosisintegralthannon-smokinggroup,therewasstatisticallysignificantdifference(P<0.05).Conclusion:Smokingcanacceleratecarotidath
7、eroscleroticprocess,makeitsearlyageofonset,exacerbations.Atthesametime,smokingcannotonlydirectlyaffectthecarotidatherosclerosis,theriskfactorshaveasignificanteffect,riskfactorsinteract,acceleratedprogressionofcarotidatherosclerosis.Tobaccosmokeasfire,heat,turbidity,poisonforacomplex
8、pathogenicfactors,l
