基于喹诺酮药物的新型配合物的合成、结构与性质分析

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1、ABSTRACTSynthese，StructuresandPropertiesStudyofNovelCoordinationPolymersBaseonMetal-·QuinoloneCoordinationComplexesInorganicChemistrymasterPostgraduate：ShiweiYanSupervisor：ProfessorDongrongXiaoCoordinationpolymerisametal．organicframeworkwithperiodicnetworkstru

2、cturewhichisconstructedbysmallmolecularligandsandmetalionsthroughself-assembleprocess，andhas0D，1D，2Dand3Dframeworks．Coordinationpolymerhasthemildsynthesiscondition，mornkindsofmaterial，specialphysicsandchemistrycharacters(thesematerialshavepotentialapplications

3、inareassuchascatalysis，separations，storage，photoluminescence，magnetismandnonlinearmaterials)thanothercomplexes．Theaimofthisthesisistosynthesizenewmetal．drugcoordinationcompoundsonthebasisoforganicdrugs，aromaticpolycarboxylateligands，andmetalions．Wemixthemenoug

4、htoproducemetalmedicinecompoundsbythehydrothermalcondition．Theaimoftheseexperimentsaretodiscusssyntheses，structureandpropertiesofmetal．drugcomplexeswithallkindsofligands，analysisinfluenceofligandsandmetalionsOntheformationofthemetal-drugcomplexesandtoexploreth

5、erelationshipsbetwe：enstructureandpropertiesforthesenowcompounds．Wehavepreparednewmetal．drugcomplexesonthebasisofhydrothermaltechniqueandstructurallycharacterizedbVelementalanalyses，IR，EPR，XPS，XRPD，TGandsinglecrystalX．raydiffractions．Thethermalstabilities，magn

6、eticpropertiesandfluorescentactivityofthesecompoundshavebeenstudied。Finally,wehavechosenppaH(piperamicacid)，lomeH(10mefloxacin)，norfH(norfloxacin)saraH(sarafloxacin)andSOonquinoloneorganicdrugsunderundersterdingandanalyzingthetheorycarefully,withlengthdifferen

7、tfragrantcarboxylicacidsuchas1,3，5-H3btc，1,4一H2bdc，1,3一H2bdc，H2sdbaandH2bpdc．Westirredthemixtureandaddthemetalsalttothem，toprepareMOFswithobviouscharacteristicoftheirstructures．Wealsomademanytesttothem．Forexample，infrared，thermogravimetry,XRPDspectrumaswellase

8、lementanalysisandSOon．Moreover,weiii西南大学硕士学位论文tooktheFLtosomecrystals．Cd(1，4一bdc)(LomeH)]’1．25H20[Zn(sdba)(Hppa)]‘1．5H20[Cd2(Hppa)2(1，3-bdc)2]．4．25H20[Zn(norfl-I)(1,4-bdc)】[Zn(Hppa