[麻省理工出版社丛书].MIT.Press.-.Multiagent.Systems.-.A.Modern.Approach.to.Distributed.Artificial.Intelligence

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1、BioinformaticsAdaptiveComputationandMachineLearningThomasDietterich,EditorChristopherBishop,DavidHeckerman,MichaelJordan,andMichaelKearns,AssociateEditorsBioinformatics:TheMachineLearningApproach,PierreBaldiandSørenBrunakReinforcementLearning:AnIntroduction,RichardS.SuttonandAndrewG.BartoPie

2、rreBaldiSørenBrunakBioinformaticsTheMachineLearningApproachABradfordBookTheMITPressCambridge,MassachusettsLondon,England
c2001MassachusettsInstituteofTechnologyAllrightsreserved.Nopartofthisbookmaybereproducedinanyformbyanyelectronicormechanicalmeans(includingphotocopying,recording,orinforma

3、tionstorageandretrieval)withoutpermissioninwritingfromthepublisher.ThisbookwassetinLucidabytheauthorsandwasprintedandboundintheUnitedStatesofAmerica.LibraryofCongressCataloging-in-PublicationDataBaldi,Pierre.Bioinformatics:themachinelearningapproach/PierreBaldi,SørenBrunak.—2nded.p.cm.—(Adap

4、tivecomputationandmachinelearning)"ABradfordBook"Includesbibliographicalreferences(p.).ISBN0-262-02506-X(hc.:alk.paper)1.Bioinformatics.2.Molecularbiology—Computersimulation.3.Molecularbiology—Mathematicalmodels.4.Neuralnetworks(Computerscience).5.Machinelearning.6.Markovprocesses.I.Brunak,S

5、øren.II.Title.III.Series.QH506.B352001572.80113—dc212001030210SeriesForewordThefirstbookinthenewseriesonAdaptiveComputationandMachineLearn-ing,PierreBaldiandSørenBrunak’sBioinformaticsprovidesacomprehensiveintroductiontotheapplicationofmachinelearninginbioinformatics.Thedevelopmentoftechniq

6、uesforsequencingentiregenomesisprovidingastro-nomicalamountsofDNAandproteinsequencedatathathavethepotentialtorevolutionizebiology.Toanalyzethisdata,newcomputationaltoolsareneeded—toolsthatapplymachinelearningalgorithmstofitcomplexstochas-ticmodels.BaldiandBrunakprovideaclearandunifiedtreatment

7、ofstatisti-calandneuralnetworkmodelsforbiologicalsequencedata.Studentsandre-searchersinthefieldsofbiologyandcomputersciencewillfindthisavaluableandaccessibleintroductiontothesepowerfulnewcomputationaltechniques.Thegoalofbuildingsystemsthatcanadapttot