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1、第二十四页:Metabolicsyndromehasbeenassociatedwithanincreasedriskofprevalentstroke.代谢综合征已与风险增加的普遍中风。IntheNationalHealthandNutritionExaminationSurvey,among10357subjects,482在全国健康和营养调查,其中10个357个科目,482theprevalenceofmetabolicsyndromewashigherinpersonswithaself-reported代谢综合征的患病率较高的人与自我报告historyofstroke(43.5%)
2、thaninsubjectswithnohistoryofCVD(22.8%;P0.001).历史的中风(43.5%)比科目没有历史的心血管疾病(22.8%;p)。Themetabolicsyndromewasindependentlyassociatedwithstrokehistoryinall代谢综合征是独立与中风史的所有ethnicgroupsandbothsexes(OR,2.16;95%CI,0.48to3.16).民族和性别(或,2.16;95%,0.48-3.16)。Recommendations建议1.Managementofindividualcomponentsofth
3、emetabolicsyndromeisrecommended,1。管理的各个组成部分的代谢综合征的建议,includinglifestylemeasures(ie,exercise,appropriateweightloss,properdiet)包括生活方式的措施(即,适当的锻炼,体重减轻,适当的饮食)andpharmacotherapy(ie,medicationsforloweringBP,loweringlipids,glycemic和药物治疗(即药物,降低血压,降低血脂,血糖control,andantiplatelettherapy)asreflectedintheNCEPAT
4、PIIIandtheJNC7,90andasendorsedorindicatedinothersectionsofthisguideline.(Refertorelevant控制,和抗血小板治疗)中所反映的ncepatp三并捷讯7,90和认可或表明在其他部分的这一方针。(参阅相关sectionsforClassesandLevelsofEvidenceforeachrecommendation.)部分类和水平的证据,每一项建议。)2.Theeffectivenessofagentsthatameliorateaspectsoftheinsulinresistance2。代理有效性,改善方面
5、的胰岛素抵抗syndromeforreducingstrokeriskisunknown(ClassIIb;LevelofEvidenceC).综合征减少中风的风险是未知的(类防爆;水平的证据,丙)。第二十五页:AlcoholConsumption酒精消费MoststudiessuggestaJ-shapedassociationbetweenalcoholconsumptionandthe大多数研究表明一个J形酒精消费之间的联系和riskoftotalandischemicstroke,withaprotectiveeffectinlightormoderate总的风险和缺血性中风,具有保
6、护作用的轻或中度drinkersandanelevatedriskwithheavyalcoholconsumption.8,492,493,497–504In饮酒和高风险的重型酒精消费。8492493497–504contrast,alinearassociationexistsbetweenalcoholconsumptionandriskof相反,一个线性协会之间的酒精消费和风险hemorrhagicstroke.LighttomoderatealcoholconsumptionisassociatedwithgreaterlevelsofHDLcholesterol,507–509r
7、educedplateletaggregation,lowerfibrinogenconcentrations,andincreasedinsulinsensitivityandglucosemetabolism.Heavyalcoholconsumptioncanresultinhypertension,hypercoagulability,reducedcerebralbloodflow,andincre