中药对荷瘤鼠细胞免疫及体液免疫影响的实验观察

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1、学位论文中药对荷瘤鼠细胞免疫及体液免疫影响的实验观察敖勇峰指导教师姓名：扬松洼教授申请学位级别：亟±专业名称：虫医盈笾型堂论文提交时间：2012—4—10论文答辩时间：2012—5—12二O一二年五月盛都生医药太堂亟±j金塞中文摘要一一一HIⅧI／I／I／HI／J／／／HI／／I／／ll。l／／／I／。HI／19lll／ll恶性骨肿瘤是严重危害人类健康及生命的疾病，尤其是大多数恶性骨肿瘤发生-T青少年的人群，治疗效果较差，从而使的对骨肿瘤的研究成为了目前医学领域关注的热点之一。情况及小鼠死亡率，眼球取血，离心取血清，用Elissa试

2、剂盒测细胞免疫CD4、CD8、体液免疫C3、C4、免疫球蛋白情况，取血后处死小鼠解剖测实体瘤直径，计算肿瘤抑制率。生存质量；对荷S180动物肿瘤的生长有明显抑制作用，对荷瘤小鼠的免疫器官有一定的保护作用并且随着药量的增加，抑制率也增加：对荷瘤小鼠细胞免疫功能有明显的提高作用，降低荷瘤小鼠体液免疫不明显，能够调节肿瘤微环境。关键词：苁蓉人参麦冬细胞免疫体液免疫抑瘤率死亡率AbstractBackground：MalignantboBetumorisadiseaseofseriousharmtohumanhealthandlife，es

3、peciallythemajorityofmalignantbonetumorsoccurinadolescentspopulation，poortreatment，inordertomakethestudyofbonetumorstobecomeoneofthefocusofattentionofthemedicalfield．China’Straditionalmedicinehasauniquetheoryinanti—tumortreatment．Naturalmedicinebutalsoforitswiderangeof

4、efficacy，precise，lowtoxicity，widerangeofdomesticandinternationalconcern．Atpresent，theanti—tumoractiveingredientextractedfromtraditionalChinesemedicineiSalsoincreasinglyreceiveattention，whichismostlyplantextracts．Experimentsandclinicalstudiesofanti—tumoreffectofChinesem

5、edicines，therearealSOreportedsingleherbandcompoundintheaffirmationofeffectofanti—tumor。basedontheaffirmationoftraditionalChinesemedicineincancertherapy，combinedwithmodernmedicine，immunefunctionintumoranimportantroleinexperimentalstudiesprovidestrongtheoreticalbasiSfort

6、heclinicaltreatmentofbonetumors，bonetumorswillalsobeofgreatsignificance．Objective：BasedonthetheoryoftraditiofialChinesemedicineincancertherapy，”therousing”observed”uphold”traditionalChinesemedicine(Renshen，Maidong，Congrong)differencesincellularimmunityandhumoralimmunit

7、yoftumor—。bearingmiceusingtopromotecellularimmunityroleinenhancingthecapacityandresistanceofhumantumorsuppressor；promotetheirapplicationininfectiousdiseasesthroughitsimpactonhumoralimmunity，whileavoidingtoaggravateorcausetumorstospreadandsideeffectshaveimportantsignifi

8、canceforimprovingtheclinicalefficacy．Andthesamedrugatthesametimeobservethedifferentreactionsanddifferencesintheroleof