滋养细胞notch信号通路在子痫前期发病机制中的研究

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1、分类号学号_M200975819__学校代码___10487____密级硕士学位论文滋养细胞Notch信号通路在子痫前期发病机制中的研究学位申请人：张娜学位专业：妇产科学指导教师：乔福元教授答辩日期：2012年5月ADissertationSubmittedinPartialFulfillmentoftheRequirementsfortheDegreeofMasterofmedicineResearchonNotchSignalingPathwayofTrophoblastsinPathoge

2、nesisofPreeclampsiaCandidate:ZhangNaSupervisor:Prof.QiaoFuyuanMajor:ObstetricsandGynecologyHuazhongUniversityofScience&TechnologyWuhan,Hubei430074,P.R.ChinaMay,2012独创性声明本人郑重声明，本学位论文是本人在导师指导下进行的研究工作及取得的研究成果的总结。尽我所知，除文中已经标明引用的内容外，本论文不包含任何其他个人或集体已经发表或撰写

3、过的研究成果。对本文的研究做出贡献的个人和集体，均已在文中以明确方式标明。本人完全意识到本人将承担本声明引起的一切法律后果。学位论文作者签名：日期：年月日学位论文版权使用授权书本学位论文作者完全了解学校有关保留、使用学位论文的规定，即：学校有权保留并向国家有关部门或机构送交论文的复印件和电子版，允许论文被查阅和借阅。本人授权华中科技大学可以将本学位论文的全部或部分内容编入有关数据库进行检索，可以采用影印、缩印或扫描等复制手段保存和汇编本学位论文。保密□，在_____年解密后适用本授权书。本论文属

4、于不保密□。（请在以上方框内打“√”）学位论文作者签名：指导教师签名：日期：年月日日期：年月日目录英文缩写及中文对照··························································1中文摘要·········································································2ABSTRACT···············································

5、······················3滋养细胞Notch信号通路在子痫前期发病机制中的研究前言············································································4材料与方法······································································8结果············································

6、································13讨论············································································17参考文献·········································································19综述·······················································

7、························21论文缺氧对滋养细胞Notch信号通路的影响·························33致谢···············································································39华中科技大学硕士学位论文英文缩写及中文对照英文缩写英文全称中文全称PBSphosphatebufferedsaline磷酸盐缓冲液RT-PCRreversetranscriptase-p

8、olymerasechain逆转录聚合酶链式反应reactionRT-qPCRreal-timequantitativepolymerasechain实时荧光定量PCRreactionODopticaldensity光密度GAPDHglyceraldehyde-3-phosphatedehydrogenase甘油醛-3-磷酸脱氢酶cDNAcomplementaryDNA互补DNAmRNAmessengerRNA信使RNACTBcytotrophoblast细胞滋养细胞STBsyncytiotro