多发性硬化患者的注意损害和事件相关电位改变的特点

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1、groupwerestatisticallylowerthanthoseofthenormalcontrolgroup．AndintheMoCAtest，theMoCAscoresinrecentmemory,attention，informationprocessingspeedandvisualspatialabilityexecutivefunctionoftheMSpatientwerealsolowerthanthoseofthenormalcontrolgroup．3．Computeraidedneuralpsyc

2、hologytestresultsshowed，1)IntheContinuousPerformanceTask(CPT)，theMSpatientcomparedwitllthenormalcontrolgroup，theaverageresponsetimewasextending，andthefalsenegativerateincreasedinthesevereincreasedsignificantly．Thedifferenceswerestatisticallysignificant．Sustainedatte

3、ntionWasdamagedobviously．2)intheStrooptest，theMSpatientwerecomparedwiththenormalcontrolgroup，reactiontimewereprolonged，interferedeffectwereincreased，butthedifferenceswerenotstatisticallysignificant．TheselectiveattentionofMSpatientwasnotobviouslydamaged．3)Inthepartof

4、TMT-B，theMSpatientcomparedwiththenormalcontrolgroup，thenumberoftime—consumingincreasedsignificantly．Thedifferencewasstatisticallysignificant．TheMetastaticattentionoftheMSpatientwasdamagedobviously．4)InthePASAT,comparedwiththenormalcontrolgroup，thescoresoftheMSpatien

5、tdecreased．Thedifferencewasstatisticallysignificant．ThedividedattentionoftheMSpatientwasdamagedobviously．4．Event—relatedpotentialsdemandthatintheMSpatientgroup，thelatencyofN2，P3，CNVwereprolonged，andthevolatilitydecreased．5．significantly．5．Thecorrelationanalysis：(1)P

6、300，CNVandCPT：1)ThecorrelationanalysisshowedthatthelatencyofN2，thelatencyandamplitudeofP3andCNVhavegoodcorrelationwithCPT．TherewasapositivecorrelationbetweenthelatencyofN2，P3，EWandthereactiontimeinCPToftheMSpatientgroup．Therewasanegativecorrelationbetweentheamplitud

7、eofP3andEW，theareaofEWandthereactiontimeinCPT．2)ThecorrelationanalysisshowedthatthelatencyofN2，thelatencyandamplitudeofP3andthelatencyandamplitudeandtheareaofEWhadgoodcorrelationwithCPT．TherewasapositivecorrelationbetweenthelatencyofN2，P3andthefalsenegativerateinCPT

8、oftheMSpatientgroup．TherewasanegativecorrelationbetweentheamplitudeoftheP3andEWandtheareaofEWandthefalsenegativerateinCPT．(2)P300，CNVandTM