芪苈强心汤治疗左室射血分数正常的心力衰竭（中医气虚血瘀型）的疗效观察

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1、提要目的：观察苈强心汤治疗左室射血分数正常的心力衰竭（气虚血瘀型）的临床疗效，并探讨其作用机制。方法：采用随机分组的方法，将60例符合纳入标准的患者分为试验组和对照组，每组30人。对照组采用西医常规治疗，试验组在西医常规治疗基础上加服其苈强心汤；治疗周期为3周。观察治疗前后患者主要临床症状改善情况及心功能、BNP及心脏超声相应指标变化情况。结果：试验组症状改善总有效率为93.3%，显效率为46.7%，与对照组相比有显著性差异(P<0.01)；试验组心功能改善总有效率为93.3%，显效率为36.7%，与对照组相比有显著性差异(P<0.01)；BNP试验组改善较对照组有显著的统计学差异（P<0

2、.01）；试验组E、A、E/A、IVRT等参数均有改善，较对照组有显著的统计学差异（P<0.01）。结论：芪苈强心汤是临床治疗左室射血分数正常的心力衰竭（气虚血瘀型）的有效方剂，该方可有效提高患者心功能，并提高生活质量，值得临床广泛应用。关键词芪苈强心汤；左室射血分数正常的心力衰竭；气虚血瘀型；临床研究ClinicalStudyonQiLiQiangXinDecoction’sInfluencetotheheartfailurewithnormalleftventricularejectionfraction（QiXuXueYuType）Speciality:Cardiovasculard

3、isease,InternalMedicineofTCMAuthor:Wangsong5Wangsong544456678899998877766bbnmllkjhhShuaiTutor:pProfWangying.GuoWeixingAbstractObjective:ToobservethecurativeeffectofQiLiQiangXinDecoctiontotheHFNEFofQiXuXueYuType,andtoexploreitsmechanism.Methods:Intheclinicalstudy,Randomizedprinciples,sixtypatientsc

4、onformingtoStandardweredividedintotentativegroup(30cases)andcontrolgroup(30cases).Thecontrolgroupwastreatedonlybyconventionalwesternmedicine,whilethetentativegroupwastreatedbyQiLiQiangXinDecoctionaddedtotheconventionalwesternmedicine.Threeweekswasacourseoftreatment.Thechangesofmainclinicalsyndrome

5、,heartfunction,heartrate、BNPandthechangeoftheechocardiographic’indiceswereobservedbeforeandaftertreatment.Results:Patientssymptomsimprovethetotaleffectiveratewas93.3%,significantefficiencyis46.7%,comparedwiththecontrolhavesignificantdifferences(P<0.01);Patientsimprovecardiacfunctionthetotaleffecti

6、verateof93.3%,significantefficiencyis36.7%,comparedwiththecontrolhavesignificantdifferences,E、A、E/A、IVRTwereimprovelargerthanthecontrol（P<0.05）;BNPimprovegroupcomparedwithagroupofsignificantstatisticaldifferences.Conclusion:QiLiQiangXinDecoctionisaneffectivemedicamentoftreatingheartfailurewithnorm

7、alleftventricularejectionfractionofQiXuXueYuType,ThisDecoctionnotonlyregulatethefunctionofheart,butalsoimproveothersymptomsandqualityoflife.Itisworthyofwiderapplication.KeywordsQiLiQiangXinDecoction;heartfailurew